ANNUAL FORECAST IN PATIENTS WITH ACUTE ISCHEMIC STROKE: ROLE OF PATHOLOGICAL ANKLE-BRACHIAL INDEX
Aim. To study the factors associated with a poor annual prognosis in patients with acute stroke and prognostic role of pathological ankle-brachial index (ABI).Material and methods. The study included 345 patients (age 63.6±7.8 years, 181 males and 164 females) with ischemic stroke that were observed...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2017-01-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/1364 |
| _version_ | 1797232197960204288 |
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| author | A. N. Sumin J. A. Kolmykova I. N. Kukhareva M. V. Ott N. I. Vodopyanova A. A. Morkvenas O. A. Trubnikova A. V. Kovalenko |
| author_facet | A. N. Sumin J. A. Kolmykova I. N. Kukhareva M. V. Ott N. I. Vodopyanova A. A. Morkvenas O. A. Trubnikova A. V. Kovalenko |
| author_sort | A. N. Sumin |
| collection | DOAJ |
| description | Aim. To study the factors associated with a poor annual prognosis in patients with acute stroke and prognostic role of pathological ankle-brachial index (ABI).Material and methods. The study included 345 patients (age 63.6±7.8 years, 181 males and 164 females) with ischemic stroke that were observed for 1 year. All patients were divided into 2 groups: Group 1 included patients with favorable annual outcome of stroke; Group 2 included patients that during a year had any clinical events including death. All patients underwent a standard neurological and instrumental examination including assessment of peripheral arteries status by sphygmomanometry.Results. Both groups did not differ by age and sex. The frequency of unfavorable outcomes (death, re-stroke, cardiovascular events) 1 year after ischemic stroke was 29.5%. Chronic heart failure, atrial fibrillation, previous cardiovascular events, presence of peripheral atherosclerosis, overweight were identified most commonly in Group 2. Patients of Group 2 initially had a rough neurological deficit. The pathological ABI was detected in 70.7% of patients in Group 2 vs 33.8% of patients in Group 1 (p=0.000001). A strong relationship of pathological ABI with a poor outcome of stroke was found by regression analysis.Conclusions. Detection of pathological ABI in patients with ischemic stroke makes it possible to reveal peripheral atherosclerosis and to carry out the targeted preventive measures in these patients. Risk stratification can contribute to more individual and effective secondary prevention in patients with cerebrovascular disease. |
| first_indexed | 2024-03-08T14:02:40Z |
| format | Article |
| id | doaj.art-075f2b0666f0494ab5b615417732be94 |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-04-24T15:56:27Z |
| publishDate | 2017-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-075f2b0666f0494ab5b615417732be942024-04-01T07:43:34ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532017-01-0112663864410.20996/1819-6446-2016-12-6-638-6441276ANNUAL FORECAST IN PATIENTS WITH ACUTE ISCHEMIC STROKE: ROLE OF PATHOLOGICAL ANKLE-BRACHIAL INDEXA. N. Sumin0J. A. Kolmykova1I. N. Kukhareva2M. V. Ott3N. I. Vodopyanova4A. A. Morkvenas5O. A. Trubnikova6A. V. Kovalenko7Research Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesAim. To study the factors associated with a poor annual prognosis in patients with acute stroke and prognostic role of pathological ankle-brachial index (ABI).Material and methods. The study included 345 patients (age 63.6±7.8 years, 181 males and 164 females) with ischemic stroke that were observed for 1 year. All patients were divided into 2 groups: Group 1 included patients with favorable annual outcome of stroke; Group 2 included patients that during a year had any clinical events including death. All patients underwent a standard neurological and instrumental examination including assessment of peripheral arteries status by sphygmomanometry.Results. Both groups did not differ by age and sex. The frequency of unfavorable outcomes (death, re-stroke, cardiovascular events) 1 year after ischemic stroke was 29.5%. Chronic heart failure, atrial fibrillation, previous cardiovascular events, presence of peripheral atherosclerosis, overweight were identified most commonly in Group 2. Patients of Group 2 initially had a rough neurological deficit. The pathological ABI was detected in 70.7% of patients in Group 2 vs 33.8% of patients in Group 1 (p=0.000001). A strong relationship of pathological ABI with a poor outcome of stroke was found by regression analysis.Conclusions. Detection of pathological ABI in patients with ischemic stroke makes it possible to reveal peripheral atherosclerosis and to carry out the targeted preventive measures in these patients. Risk stratification can contribute to more individual and effective secondary prevention in patients with cerebrovascular disease.https://www.rpcardio.online/jour/article/view/1364ankle-brachial indexstrokerisk factorsstroke outcomes |
| spellingShingle | A. N. Sumin J. A. Kolmykova I. N. Kukhareva M. V. Ott N. I. Vodopyanova A. A. Morkvenas O. A. Trubnikova A. V. Kovalenko ANNUAL FORECAST IN PATIENTS WITH ACUTE ISCHEMIC STROKE: ROLE OF PATHOLOGICAL ANKLE-BRACHIAL INDEX Рациональная фармакотерапия в кардиологии ankle-brachial index stroke risk factors stroke outcomes |
| title | ANNUAL FORECAST IN PATIENTS WITH ACUTE ISCHEMIC STROKE: ROLE OF PATHOLOGICAL ANKLE-BRACHIAL INDEX |
| title_full | ANNUAL FORECAST IN PATIENTS WITH ACUTE ISCHEMIC STROKE: ROLE OF PATHOLOGICAL ANKLE-BRACHIAL INDEX |
| title_fullStr | ANNUAL FORECAST IN PATIENTS WITH ACUTE ISCHEMIC STROKE: ROLE OF PATHOLOGICAL ANKLE-BRACHIAL INDEX |
| title_full_unstemmed | ANNUAL FORECAST IN PATIENTS WITH ACUTE ISCHEMIC STROKE: ROLE OF PATHOLOGICAL ANKLE-BRACHIAL INDEX |
| title_short | ANNUAL FORECAST IN PATIENTS WITH ACUTE ISCHEMIC STROKE: ROLE OF PATHOLOGICAL ANKLE-BRACHIAL INDEX |
| title_sort | annual forecast in patients with acute ischemic stroke role of pathological ankle brachial index |
| topic | ankle-brachial index stroke risk factors stroke outcomes |
| url | https://www.rpcardio.online/jour/article/view/1364 |
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