Serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucoma
Purpose: Two diabetic case reports of serous retinal detachment (SRD) accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for neovascular glaucoma (NVG). Observations: Case 1: A 66-year-old female with stage 3 NVG and decreased vision acuity in the left eye. After trabeculectomy...
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| Format: | Article |
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Elsevier
2020-06-01
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| Series: | American Journal of Ophthalmology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993620300530 |
| _version_ | 1818337989454987264 |
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| author | Sakurako Shimokawa Shintaro Nakao Yusuke Murakami Yasuhiro Ikeda Koh-Hei Sonoda |
| author_facet | Sakurako Shimokawa Shintaro Nakao Yusuke Murakami Yasuhiro Ikeda Koh-Hei Sonoda |
| author_sort | Sakurako Shimokawa |
| collection | DOAJ |
| description | Purpose: Two diabetic case reports of serous retinal detachment (SRD) accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for neovascular glaucoma (NVG). Observations: Case 1: A 66-year-old female with stage 3 NVG and decreased vision acuity in the left eye. After trabeculectomy, postoperative laser suture lysis (LSL) resulted in development of hypotony maculopathy, followed by pachychoroid and SRD. Injection of C3F8 gas in the anterior chamber was unsuccessful and transconjunctival scleral re-suturing was performed. Intraocular pressure (IOP) consequently increased and SRD improved. Case 2: A 60-year-old man with stage 2 NVG and decreased vision acuity in the right eye. Trabeculectomy was uneventful, but postoperative LSL also resulted in development of hypotony maculopathy followed by pachychroid and SRD. Intravitreal bevacizumab injection had no effect and transconjunctival flap re-suturing was performed. IOP consequently increased and SRD improved. Conclusions: SRD accompanied by pachychoroid was observed in hypotony maculopathy in diabetic cases. VEGF-independent exudative change in hypotony maculopathy may be due to hydrostatic pressure elevation in choroidal blood vessels based on Starling's hypothesis with the consequent breakdown of retinal pigment epithelium barrier in diabetic patients. |
| first_indexed | 2024-12-13T15:03:59Z |
| format | Article |
| id | doaj.art-076106a093a34705b3bdbd3ae8bfe077 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-13T15:03:59Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-076106a093a34705b3bdbd3ae8bfe0772022-12-21T23:41:04ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362020-06-0118Serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucomaSakurako Shimokawa0Shintaro Nakao1Yusuke Murakami2Yasuhiro Ikeda3Koh-Hei Sonoda4Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Corresponding author. Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Department of Ophthalmology, Faculty of Medicine, University of Miyazaki, Miyazaki, JapanDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, JapanPurpose: Two diabetic case reports of serous retinal detachment (SRD) accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for neovascular glaucoma (NVG). Observations: Case 1: A 66-year-old female with stage 3 NVG and decreased vision acuity in the left eye. After trabeculectomy, postoperative laser suture lysis (LSL) resulted in development of hypotony maculopathy, followed by pachychoroid and SRD. Injection of C3F8 gas in the anterior chamber was unsuccessful and transconjunctival scleral re-suturing was performed. Intraocular pressure (IOP) consequently increased and SRD improved. Case 2: A 60-year-old man with stage 2 NVG and decreased vision acuity in the right eye. Trabeculectomy was uneventful, but postoperative LSL also resulted in development of hypotony maculopathy followed by pachychroid and SRD. Intravitreal bevacizumab injection had no effect and transconjunctival flap re-suturing was performed. IOP consequently increased and SRD improved. Conclusions: SRD accompanied by pachychoroid was observed in hypotony maculopathy in diabetic cases. VEGF-independent exudative change in hypotony maculopathy may be due to hydrostatic pressure elevation in choroidal blood vessels based on Starling's hypothesis with the consequent breakdown of retinal pigment epithelium barrier in diabetic patients.http://www.sciencedirect.com/science/article/pii/S2451993620300530Vascular endothelial growth factorBevacizumabOCTBlood-retinal barrier |
| spellingShingle | Sakurako Shimokawa Shintaro Nakao Yusuke Murakami Yasuhiro Ikeda Koh-Hei Sonoda Serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucoma American Journal of Ophthalmology Case Reports Vascular endothelial growth factor Bevacizumab OCT Blood-retinal barrier |
| title | Serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucoma |
| title_full | Serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucoma |
| title_fullStr | Serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucoma |
| title_full_unstemmed | Serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucoma |
| title_short | Serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucoma |
| title_sort | serous retinal detachment accompanied by pachychoroid in hypotony maculopathy after trabeculectomy for diabetic neovascular glaucoma |
| topic | Vascular endothelial growth factor Bevacizumab OCT Blood-retinal barrier |
| url | http://www.sciencedirect.com/science/article/pii/S2451993620300530 |
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