Immune perturbation network identifies an EMT subtype with chromosomal instability and tumor immune-desert microenvironment

Immune perturbation network identifies an EMT subtype with chromosomal instability and tumor immune-desert microenvironment

Summary: Most gastric cancer (GC) subtypes are identified through transcriptional profiling overlooking dynamic changes and interactions in gene expression. Based on the background network of global immune genes, we constructed sample-specific edge-perturbation matrices and identified four molecular...

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Bibliographic Details
Main Authors: Hui Xu, Xinyu Fu, Ben Liu, Siyuan Weng, Chunguang Guo, Libo Quan, Long Liu, Libo Wang, Zhe Xing, Quan Cheng, Peng Luo, Kexin Chen, Zaoqu Liu, Xinwei Han
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Oncology
Immunology
Genomic analysis
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301948X

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http://www.sciencedirect.com/science/article/pii/S258900422301948X

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