Immune perturbation network identifies an EMT subtype with chromosomal instability and tumor immune-desert microenvironment
Summary: Most gastric cancer (GC) subtypes are identified through transcriptional profiling overlooking dynamic changes and interactions in gene expression. Based on the background network of global immune genes, we constructed sample-specific edge-perturbation matrices and identified four molecular...
Main Authors: | Hui Xu, Xinyu Fu, Ben Liu, Siyuan Weng, Chunguang Guo, Libo Quan, Long Liu, Libo Wang, Zhe Xing, Quan Cheng, Peng Luo, Kexin Chen, Zaoqu Liu, Xinwei Han |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-10-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422301948X |
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