Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses
Viral infections have recently emerged not only as a health threat to people but rapidly became the cause of universal fatality on a large scale. Nanomaterials comprising functionalized nanoparticles (NPs) and quantum dots and nanotechnology-associated innovative detection methods, vaccine design, a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-05-01
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| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/10/6/1072 |
| _version_ | 1797566474725883904 |
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| author | Mahmoud Nasrollahzadeh Mohaddeseh Sajjadi Ghazaleh Jamalipour Soufi Siavash Iravani Rajender S. Varma |
| author_facet | Mahmoud Nasrollahzadeh Mohaddeseh Sajjadi Ghazaleh Jamalipour Soufi Siavash Iravani Rajender S. Varma |
| author_sort | Mahmoud Nasrollahzadeh |
| collection | DOAJ |
| description | Viral infections have recently emerged not only as a health threat to people but rapidly became the cause of universal fatality on a large scale. Nanomaterials comprising functionalized nanoparticles (NPs) and quantum dots and nanotechnology-associated innovative detection methods, vaccine design, and nanodrug production have shown immense promise for interfacing with pathogenic viruses and restricting their entrance into cells. These viruses have been scrutinized using rapid diagnostic detection and therapeutic interventional options against the caused infections including vaccine development for prevention and control. Coronaviruses, namely SARS-CoV, MERS-CoV, and SARS-CoV-2, have endangered human life, and the COVID-19 (caused by SARS-CoV-2) outbreak has become a perilous challenge to public health globally with huge accompanying morbidity rates. Thus, it is imperative to expedite the drug and vaccine development efforts that would help mitigate this pandemic. In this regard, smart and innovative nano-based technologies and approaches encompassing applications of green nanomedicine, bio-inspired methods, multifunctional bioengineered nanomaterials, and biomimetic drug delivery systems/carriers can help resolve the critical issues regarding detection, prevention, and treatment of viral infections. This perspective review expounds recent nanoscience advancements for the detection and treatment of viral infections with focus on coronaviruses and encompasses nano-based formulations and delivery platforms, nanovaccines, and promising methods for clinical diagnosis, especially regarding SARS-CoV-2. |
| first_indexed | 2024-03-10T19:28:20Z |
| format | Article |
| id | doaj.art-07627203f2b24abb8d5fa452cf09e7ff |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T19:28:20Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-07627203f2b24abb8d5fa452cf09e7ff2023-11-20T02:20:49ZengMDPI AGNanomaterials2079-49912020-05-01106107210.3390/nano10061072Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on CoronavirusesMahmoud Nasrollahzadeh0Mohaddeseh Sajjadi1Ghazaleh Jamalipour Soufi2Siavash Iravani3Rajender S. Varma4Department of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, IranDepartment of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, IranRadiology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746 73461, IranFaculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746 73461, IranRegional Centre of Advanced Technologies and Materials, Palacký University in Olomouc, Šlechtitelů 27, 783 71, CZ-779 00 Olomouc, Czech RepublicViral infections have recently emerged not only as a health threat to people but rapidly became the cause of universal fatality on a large scale. Nanomaterials comprising functionalized nanoparticles (NPs) and quantum dots and nanotechnology-associated innovative detection methods, vaccine design, and nanodrug production have shown immense promise for interfacing with pathogenic viruses and restricting their entrance into cells. These viruses have been scrutinized using rapid diagnostic detection and therapeutic interventional options against the caused infections including vaccine development for prevention and control. Coronaviruses, namely SARS-CoV, MERS-CoV, and SARS-CoV-2, have endangered human life, and the COVID-19 (caused by SARS-CoV-2) outbreak has become a perilous challenge to public health globally with huge accompanying morbidity rates. Thus, it is imperative to expedite the drug and vaccine development efforts that would help mitigate this pandemic. In this regard, smart and innovative nano-based technologies and approaches encompassing applications of green nanomedicine, bio-inspired methods, multifunctional bioengineered nanomaterials, and biomimetic drug delivery systems/carriers can help resolve the critical issues regarding detection, prevention, and treatment of viral infections. This perspective review expounds recent nanoscience advancements for the detection and treatment of viral infections with focus on coronaviruses and encompasses nano-based formulations and delivery platforms, nanovaccines, and promising methods for clinical diagnosis, especially regarding SARS-CoV-2.https://www.mdpi.com/2079-4991/10/6/1072nanotechnologynanoparticlesquantum dotsgraphene oxidenanovaccinescoronaviruses |
| spellingShingle | Mahmoud Nasrollahzadeh Mohaddeseh Sajjadi Ghazaleh Jamalipour Soufi Siavash Iravani Rajender S. Varma Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses Nanomaterials nanotechnology nanoparticles quantum dots graphene oxide nanovaccines coronaviruses |
| title | Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses |
| title_full | Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses |
| title_fullStr | Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses |
| title_full_unstemmed | Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses |
| title_short | Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses |
| title_sort | nanomaterials and nanotechnology associated innovations against viral infections with a focus on coronaviruses |
| topic | nanotechnology nanoparticles quantum dots graphene oxide nanovaccines coronaviruses |
| url | https://www.mdpi.com/2079-4991/10/6/1072 |
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