Recent status and knowledge on the Re-emergence of Monkeypox Disease
Insights into the Monkeypox (MPX) disease, causative virus, its transmission including possible reservoir(s) is scattered. The recent outbreak of MPX disease as we begin to see a high number of cases emerging from non-endemic countries is a wake-up call for the research community. This review presen...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Scientific African |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468227623003058 |
| _version_ | 1797676195055140864 |
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| author | Kwabena Dabie Felix Adulley Essuman Jonathan Boansi Adu Ababio Emmanuel Peprah-Yamoah Mubarak Osman Yakubu Gausu Mohammed Enock Dugbatey Mensah |
| author_facet | Kwabena Dabie Felix Adulley Essuman Jonathan Boansi Adu Ababio Emmanuel Peprah-Yamoah Mubarak Osman Yakubu Gausu Mohammed Enock Dugbatey Mensah |
| author_sort | Kwabena Dabie |
| collection | DOAJ |
| description | Insights into the Monkeypox (MPX) disease, causative virus, its transmission including possible reservoir(s) is scattered. The recent outbreak of MPX disease as we begin to see a high number of cases emerging from non-endemic countries is a wake-up call for the research community. This review presents an update on the re-emergence of the MPX disease as it spreads across the globe like never before. Unlike most single-stranded RNA viruses, such as SARS-COV 2, this zoonotic disease (MPX) is caused by a double-stranded DNA virus, the Monkeypox virus. Thus, the replication machinery of the MPX virus genome is highly conserved without undergoing many changes (mutations), which usually present challenges in vaccine development. To review recent studies and reports on MPX disease, a comprehensive scientific literature search in relation to terms such as MPX disease, MPX virus, and transmission routes of MPX virus was conducted. Suspected MPX virus reservoirs, animal-to-human and three main person-to-person modes of transmission were noted to have been reported. Finally, diagnostic methods of MPX virus and treatment or prevention measures of the disease as indicated by the WHO and CDC were also reviewed. |
| first_indexed | 2024-03-11T22:25:30Z |
| format | Article |
| id | doaj.art-0767acb8362d4547bb89e26c23c76dbb |
| institution | Directory Open Access Journal |
| issn | 2468-2276 |
| language | English |
| last_indexed | 2024-03-11T22:25:30Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Scientific African |
| spelling | doaj.art-0767acb8362d4547bb89e26c23c76dbb2023-09-24T05:16:21ZengElsevierScientific African2468-22762023-09-0121e01849Recent status and knowledge on the Re-emergence of Monkeypox DiseaseKwabena Dabie0Felix Adulley1Essuman Jonathan2Boansi Adu Ababio3Emmanuel Peprah-Yamoah4Mubarak Osman5Yakubu Gausu Mohammed6Enock Dugbatey Mensah7Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, NM 87131, USA; Department of Biochemistry, University of Cape Coast, Ghana; Corresponding author.Department of Chemistry, East Tennessee State University, TN 37604, USA; Department of Biochemistry, University of Cape Coast, GhanaDepartment of Biochemistry, University of Cape Coast, GhanaDepartment of Chemistry, Kwame Nkrumah University of Science and Technology, Ghana; Department of Chemistry, University of Cape Coast, GhanaDepartment of Chemistry, East Tennessee State University, TN 37604, USA; Department of Biochemistry, University of Cape Coast, GhanaDepartment of Chemistry, East Tennessee State University, TN 37604, USADepartment of Chemistry, East Tennessee State University, TN 37604, USA; Department of Biochemistry, University of Cape Coast, GhanaDepartment of Biochemistry, University of Cape Coast, Ghana; Department of Chemistry, Virginia Polytechnic Institute and State University, United StatesInsights into the Monkeypox (MPX) disease, causative virus, its transmission including possible reservoir(s) is scattered. The recent outbreak of MPX disease as we begin to see a high number of cases emerging from non-endemic countries is a wake-up call for the research community. This review presents an update on the re-emergence of the MPX disease as it spreads across the globe like never before. Unlike most single-stranded RNA viruses, such as SARS-COV 2, this zoonotic disease (MPX) is caused by a double-stranded DNA virus, the Monkeypox virus. Thus, the replication machinery of the MPX virus genome is highly conserved without undergoing many changes (mutations), which usually present challenges in vaccine development. To review recent studies and reports on MPX disease, a comprehensive scientific literature search in relation to terms such as MPX disease, MPX virus, and transmission routes of MPX virus was conducted. Suspected MPX virus reservoirs, animal-to-human and three main person-to-person modes of transmission were noted to have been reported. Finally, diagnostic methods of MPX virus and treatment or prevention measures of the disease as indicated by the WHO and CDC were also reviewed.http://www.sciencedirect.com/science/article/pii/S2468227623003058Monkeypox (MPX)Zoonotic diseasePoxvirusMPX transmission routesReservoirs |
| spellingShingle | Kwabena Dabie Felix Adulley Essuman Jonathan Boansi Adu Ababio Emmanuel Peprah-Yamoah Mubarak Osman Yakubu Gausu Mohammed Enock Dugbatey Mensah Recent status and knowledge on the Re-emergence of Monkeypox Disease Scientific African Monkeypox (MPX) Zoonotic disease Poxvirus MPX transmission routes Reservoirs |
| title | Recent status and knowledge on the Re-emergence of Monkeypox Disease |
| title_full | Recent status and knowledge on the Re-emergence of Monkeypox Disease |
| title_fullStr | Recent status and knowledge on the Re-emergence of Monkeypox Disease |
| title_full_unstemmed | Recent status and knowledge on the Re-emergence of Monkeypox Disease |
| title_short | Recent status and knowledge on the Re-emergence of Monkeypox Disease |
| title_sort | recent status and knowledge on the re emergence of monkeypox disease |
| topic | Monkeypox (MPX) Zoonotic disease Poxvirus MPX transmission routes Reservoirs |
| url | http://www.sciencedirect.com/science/article/pii/S2468227623003058 |
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