Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies

Analysis of Pre-Analytic Factors Affecting the Success of Clinical Next-Generation Sequencing of Solid Organ Malignancies

Application of next-generation sequencing (NGS) technology to routine clinical practice has enabled characterization of personalized cancer genomes to identify patients likely to have a response to targeted therapy. The proper selection of tumor sample for downstream NGS based mutational analysis is...

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Bibliographic Details
Main Authors: Hui Chen, Rajyalakshmi Luthra, Rashmi S. Goswami, Rajesh R. Singh, Sinchita Roy-Chowdhuri
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Cancers
Subjects:
next-generation sequencing
targeted hotspot mutation analysis
pre-analytic factors
tissue qualification
Online Access:http://www.mdpi.com/2072-6694/7/3/0859

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