Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysis
ObjectiveThe purpose of this meta-analysis was to investigate the effect of high-intensity interval training (HIIT) on arterial stiffness (AS) and vascular function in persons at high risk of cardiovascular disease (CVD).MethodsWe conducted a comprehensive search of randomized controlled trials (RCT...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2024.1376861/full |
| _version_ | 1797202857184722944 |
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| author | Ping Luo Ruoshan Wu Weifeng Gao Weiyi Yan Ruixue Wang Yufang Ye |
| author_facet | Ping Luo Ruoshan Wu Weifeng Gao Weiyi Yan Ruixue Wang Yufang Ye |
| author_sort | Ping Luo |
| collection | DOAJ |
| description | ObjectiveThe purpose of this meta-analysis was to investigate the effect of high-intensity interval training (HIIT) on arterial stiffness (AS) and vascular function in persons at high risk of cardiovascular disease (CVD).MethodsWe conducted a comprehensive search of randomized controlled trials (RCTs) published in electronic databases (PubMed, Web of Science, Cochrane, Embase, and Ebsco) since their inception through October 2023 to evaluate the effect of HIIT on AS and vascular function in persons at high risk for CVD. The weighted mean difference (WMD) and 95% confidence intervals (95% CI) were calculated, and heterogeneity was assessed using the I2 test.ResultsThis study included 661 participants from 16 studies. HIIT significantly reduced pulse wave velocity (PWV) in persons at high risk for CVD [weighted mean difference (WMD), −0.62; 95% CI, −0.86–−0.38; P < 0.00001]. Subgroup analysis showed that the PWV improvement effect was better when the HIIT program was performed 2–3 times per week and the duration was controlled within 40 min [2–3 times, −0.67; 95% CI, −0.93–−0.41; P < 0.00001; time of duration, ≤40 min, −0.66; 95% CI, −0.91–−0.41; P < 0.00001]. HIIT significantly reduced systolic blood pressure (SBP, −5.43; 95% CI, −8.82–−2.04; P = 0.002), diastolic blood pressure (DPB, −2.96; 95% CI, −4.88–−1.04; P = 0.002), and resting heart rate (RHR, −4.35; 95% CI, −7.04–−1.66; P = 0.002), but had no significant effect on augmentation index (AIX, −2.14; 95% CI, −6.77–2.50; P = 0.37).ConclusionHIIT can improve PWV in high-risk individuals with CVD and reduce SBP, DBP, and RHR, but has no significant effect on AIX. HIIT can effectively improve AS and vascular function and can be recommended as an effective method to improve AS in high-risk persons with CVD.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42023471593. |
| first_indexed | 2024-04-24T08:10:06Z |
| format | Article |
| id | doaj.art-076cf4a48d394528ba4f7511794239a5 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-24T08:10:06Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-076cf4a48d394528ba4f7511794239a52024-04-17T05:00:27ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2024-04-011110.3389/fcvm.2024.13768611376861Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysisPing Luo0Ruoshan Wu1Weifeng Gao2Weiyi Yan3Ruixue Wang4Yufang Ye5School of Physical Education, Wuhan Sport University, Wuhan, ChinaSchool of Physical Education, Hunan University of Science and Technology, Xiangtan, ChinaSchool of Physical Education, Wuhan Sport University, Wuhan, ChinaSchool of Physical Education, Wuhan Sport University, Wuhan, ChinaSchool of Physical Education, Wuhan Sport University, Wuhan, ChinaSchool of Physical Education, Wuhan Sport University, Wuhan, ChinaObjectiveThe purpose of this meta-analysis was to investigate the effect of high-intensity interval training (HIIT) on arterial stiffness (AS) and vascular function in persons at high risk of cardiovascular disease (CVD).MethodsWe conducted a comprehensive search of randomized controlled trials (RCTs) published in electronic databases (PubMed, Web of Science, Cochrane, Embase, and Ebsco) since their inception through October 2023 to evaluate the effect of HIIT on AS and vascular function in persons at high risk for CVD. The weighted mean difference (WMD) and 95% confidence intervals (95% CI) were calculated, and heterogeneity was assessed using the I2 test.ResultsThis study included 661 participants from 16 studies. HIIT significantly reduced pulse wave velocity (PWV) in persons at high risk for CVD [weighted mean difference (WMD), −0.62; 95% CI, −0.86–−0.38; P < 0.00001]. Subgroup analysis showed that the PWV improvement effect was better when the HIIT program was performed 2–3 times per week and the duration was controlled within 40 min [2–3 times, −0.67; 95% CI, −0.93–−0.41; P < 0.00001; time of duration, ≤40 min, −0.66; 95% CI, −0.91–−0.41; P < 0.00001]. HIIT significantly reduced systolic blood pressure (SBP, −5.43; 95% CI, −8.82–−2.04; P = 0.002), diastolic blood pressure (DPB, −2.96; 95% CI, −4.88–−1.04; P = 0.002), and resting heart rate (RHR, −4.35; 95% CI, −7.04–−1.66; P = 0.002), but had no significant effect on augmentation index (AIX, −2.14; 95% CI, −6.77–2.50; P = 0.37).ConclusionHIIT can improve PWV in high-risk individuals with CVD and reduce SBP, DBP, and RHR, but has no significant effect on AIX. HIIT can effectively improve AS and vascular function and can be recommended as an effective method to improve AS in high-risk persons with CVD.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42023471593.https://www.frontiersin.org/articles/10.3389/fcvm.2024.1376861/fullhigh-intensity interval exercisearterial stiffnesscardiovascular diseasepulse wave velocityresting heart rateaugmentation index |
| spellingShingle | Ping Luo Ruoshan Wu Weifeng Gao Weiyi Yan Ruixue Wang Yufang Ye Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysis Frontiers in Cardiovascular Medicine high-intensity interval exercise arterial stiffness cardiovascular disease pulse wave velocity resting heart rate augmentation index |
| title | Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysis |
| title_full | Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysis |
| title_fullStr | Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysis |
| title_full_unstemmed | Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysis |
| title_short | Effects of high-intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease: a meta-analysis |
| title_sort | effects of high intensity interval exercise on arterial stiffness in individuals at risk for cardiovascular disease a meta analysis |
| topic | high-intensity interval exercise arterial stiffness cardiovascular disease pulse wave velocity resting heart rate augmentation index |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2024.1376861/full |
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