Lynch Syndrome Biopathology and Treatment: The Potential Role of microRNAs in Clinical Practice

Lynch Syndrome Biopathology and Treatment: The Potential Role of microRNAs in Clinical Practice

Lynch syndrome (LS), also known as Hereditary Non-Polyposis Colorectal Cancer (HNPCC), is an autosomal dominant cancer syndrome which causes about 2–3% of cases of colorectal carcinoma. The development of LS is due to the genetic and epigenetic inactivation of genes involved in the DNA mismatch repa...

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Bibliographic Details
Main Authors: Serena Ascrizzi, Grazia Maria Arillotta, Katia Grillone, Giulio Caridà, Stefania Signorelli, Asad Ali, Caterina Romeo, Pierfrancesco Tassone, Pierosandro Tagliaferri
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
Lynch syndrome
hereditary non-polyposis colorectal cancer
HNPCC
microRNAs
miRNAs
non-coding RNAs
Online Access:https://www.mdpi.com/2072-6694/15/15/3930

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