TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway

TBL1XR1 Ensures Balanced Neural Development Through NCOR Complex-Mediated Regulation of the MAPK Pathway

TBL1XR1 gene is associated with multiple developmental disorders presenting several neurological aspects. The relative protein is involved in the modulation of important cellular pathways and master regulators of transcriptional output, including nuclear receptor repressors, Wnt signaling, and MECP2...

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Bibliographic Details
Main Authors: Giuseppina Mastrototaro, Mattia Zaghi, Luca Massimino, Matteo Moneta, Neda Mohammadi, Federica Banfi, Edoardo Bellini, Marzia Indrigo, Giulia Fagnocchi, Anna Bagliani, Stefano Taverna, Maria Rohm, Stephan Herzig, Alessandro Sessa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TBL1XR1
NCOR
brain development
neurodevelopmental disorders
MAPK
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.641410/full

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