Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, Iran
<strong>Background:</strong> Epidemiological studies showed that vitamin D deficiency is associated with components of metabolic syndrome. <strong>Objectives:</strong> The aim of the present study was to determine the association between serum 25 hydroxyvitamin D concentratio...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2014-06-01
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| Series: | Women’s Health Bulletin |
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| Online Access: | http://womenshealthbulletin.sums.ac.ir/article_45170_bd9d783a51db21cb6d1472fcbbf96fdd.pdf |
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| author | Zamzam Paknahad Azam Ahmadi Vasmehjani Mohammad Reza Maracy |
| author_facet | Zamzam Paknahad Azam Ahmadi Vasmehjani Mohammad Reza Maracy |
| author_sort | Zamzam Paknahad |
| collection | DOAJ |
| description | <strong>Background:</strong> Epidemiological studies showed that vitamin D deficiency is associated with components of metabolic syndrome.
<strong>Objectives:</strong> The aim of the present study was to determine the association between serum 25 hydroxyvitamin D concentration and components of metabolic syndrome in Iranian adult women.
<strong>Patients and Methods:</strong> This study was comprised of 156 women aged ≥ 30 years with at least three of the five criteria of metabolic syndromes. Serum 25-hydroxyvitamin D (25 (OH)D) levels and components of the metabolic syndrome were determined. Metabolic syndrome was defined according to NCEP/ATP III criteria. The subjects were classified into three groups according to their serum concentration of 25 (OH)D.
<strong>Results:</strong> Mean of serum concentration of 25-hydroxyvitamin D was 20.5 ± 10.8 ng/mL with %54.5, 23.1% and 22.4% of subjects were deficient, insufficient and sufficient in vitamin D, respectively. After adjustment for age, BMI, physical activity, and ANCOVA, fasting blood sugar concentration was shown to be inversely associated with serum 25 (OH)D (P = 0.004). On the other hand HDL-C showed significant correlation across different groups of vitamin D status (P = 0.014). Waist Circumference had favorable changes, without any statistically significant correlation. Also no significant association was observed between other components of metabolic syndrome and 25 (OH)D in different groups.
<strong>Conclusions:</strong> The components of metabolic syndrome are influenced by serum 25 (OH)D concentrations. The finding of this investigation revealed that FBS and HDL-C concentrations related to serum 25 (OH)D. Therefore, further longitudinal studies and randomized clinical trials are necessary to determine the possible role of vitamin D in prevention of diabetes and cardiovascular disease. |
| first_indexed | 2024-12-22T20:21:09Z |
| format | Article |
| id | doaj.art-076f306e6c67438e8fb53c558acdee8a |
| institution | Directory Open Access Journal |
| issn | 2345-5136 2382-9990 |
| language | English |
| last_indexed | 2024-12-22T20:21:09Z |
| publishDate | 2014-06-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Women’s Health Bulletin |
| spelling | doaj.art-076f306e6c67438e8fb53c558acdee8a2022-12-21T18:13:51ZengShiraz University of Medical SciencesWomen’s Health Bulletin2345-51362382-99902014-06-01121610.17795/whb-2012445170Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, IranZamzam Paknahad0Azam Ahmadi Vasmehjani1Mohammad Reza Maracy2Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, IR Iran|Department of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, IR IranDepartment of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, IR IranDepartment of Epidemiology and Biostatistics,Faculty of Health, Isfahan University of Medical Sciences, Isfahan, IR Iran<strong>Background:</strong> Epidemiological studies showed that vitamin D deficiency is associated with components of metabolic syndrome. <strong>Objectives:</strong> The aim of the present study was to determine the association between serum 25 hydroxyvitamin D concentration and components of metabolic syndrome in Iranian adult women. <strong>Patients and Methods:</strong> This study was comprised of 156 women aged ≥ 30 years with at least three of the five criteria of metabolic syndromes. Serum 25-hydroxyvitamin D (25 (OH)D) levels and components of the metabolic syndrome were determined. Metabolic syndrome was defined according to NCEP/ATP III criteria. The subjects were classified into three groups according to their serum concentration of 25 (OH)D. <strong>Results:</strong> Mean of serum concentration of 25-hydroxyvitamin D was 20.5 ± 10.8 ng/mL with %54.5, 23.1% and 22.4% of subjects were deficient, insufficient and sufficient in vitamin D, respectively. After adjustment for age, BMI, physical activity, and ANCOVA, fasting blood sugar concentration was shown to be inversely associated with serum 25 (OH)D (P = 0.004). On the other hand HDL-C showed significant correlation across different groups of vitamin D status (P = 0.014). Waist Circumference had favorable changes, without any statistically significant correlation. Also no significant association was observed between other components of metabolic syndrome and 25 (OH)D in different groups. <strong>Conclusions:</strong> The components of metabolic syndrome are influenced by serum 25 (OH)D concentrations. The finding of this investigation revealed that FBS and HDL-C concentrations related to serum 25 (OH)D. Therefore, further longitudinal studies and randomized clinical trials are necessary to determine the possible role of vitamin D in prevention of diabetes and cardiovascular disease.http://womenshealthbulletin.sums.ac.ir/article_45170_bd9d783a51db21cb6d1472fcbbf96fdd.pdfblood fasting sugarwomenvitamin dmetabolic syndrome |
| spellingShingle | Zamzam Paknahad Azam Ahmadi Vasmehjani Mohammad Reza Maracy Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, Iran Women’s Health Bulletin blood fasting sugar women vitamin d metabolic syndrome |
| title | Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, Iran |
| title_full | Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, Iran |
| title_fullStr | Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, Iran |
| title_full_unstemmed | Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, Iran |
| title_short | Association of Serum 25-Hydroxyvitamin D Levels With Markers of Metabolic Syndrome in Adult Women in Ramsar, Iran |
| title_sort | association of serum 25 hydroxyvitamin d levels with markers of metabolic syndrome in adult women in ramsar iran |
| topic | blood fasting sugar women vitamin d metabolic syndrome |
| url | http://womenshealthbulletin.sums.ac.ir/article_45170_bd9d783a51db21cb6d1472fcbbf96fdd.pdf |
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