Glaucoma Treatment and Hydrogel: Current Insights and State of the Art
Aqueous gels formulated using hydrophilic polymers (hydrogels) and those based on stimuli-responsive polymers (in situ gelling or gel-forming systems) attract increasing interest in the treatment of several eye diseases. Their chemical structure enables them to incorporate various ophthalmic medicat...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
|
| Series: | Gels |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2310-2861/8/8/510 |
| _version_ | 1827617830885916672 |
|---|---|
| author | Antonio Maria Fea Cristina Novarese Paolo Caselgrandi Giacomo Boscia |
| author_facet | Antonio Maria Fea Cristina Novarese Paolo Caselgrandi Giacomo Boscia |
| author_sort | Antonio Maria Fea |
| collection | DOAJ |
| description | Aqueous gels formulated using hydrophilic polymers (hydrogels) and those based on stimuli-responsive polymers (in situ gelling or gel-forming systems) attract increasing interest in the treatment of several eye diseases. Their chemical structure enables them to incorporate various ophthalmic medications, achieving their optimal therapeutic doses and providing more clinically relevant time courses (weeks or months as opposed to hours and days), which will inevitably reduce dose frequency, thereby improving patient compliance and clinical outcomes. Due to its chronic course, the treatment of glaucoma may benefit from applying gel technologies as drug-delivering systems and as antifibrotic treatment during and after surgery. Therefore, our purpose is to review current applications of ophthalmic gelling systems with particular emphasis on glaucoma. |
| first_indexed | 2024-03-09T09:55:57Z |
| format | Article |
| id | doaj.art-07733a858f7c4053b91b233445cf7927 |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-09T09:55:57Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-07733a858f7c4053b91b233445cf79272023-12-01T23:43:42ZengMDPI AGGels2310-28612022-08-018851010.3390/gels8080510Glaucoma Treatment and Hydrogel: Current Insights and State of the ArtAntonio Maria Fea0Cristina Novarese1Paolo Caselgrandi2Giacomo Boscia3Department of Ophthalmology, University of Turin, Via Cherasco 23, 10126 Turin, ItalyDepartment of Ophthalmology, University of Turin, Via Cherasco 23, 10126 Turin, ItalyDepartment of Ophthalmology, University of Turin, Via Cherasco 23, 10126 Turin, ItalyDepartment of Ophthalmology, University of Turin, Via Cherasco 23, 10126 Turin, ItalyAqueous gels formulated using hydrophilic polymers (hydrogels) and those based on stimuli-responsive polymers (in situ gelling or gel-forming systems) attract increasing interest in the treatment of several eye diseases. Their chemical structure enables them to incorporate various ophthalmic medications, achieving their optimal therapeutic doses and providing more clinically relevant time courses (weeks or months as opposed to hours and days), which will inevitably reduce dose frequency, thereby improving patient compliance and clinical outcomes. Due to its chronic course, the treatment of glaucoma may benefit from applying gel technologies as drug-delivering systems and as antifibrotic treatment during and after surgery. Therefore, our purpose is to review current applications of ophthalmic gelling systems with particular emphasis on glaucoma.https://www.mdpi.com/2310-2861/8/8/510hydrogeldrug deliveryglaucomananoparticlesophthalmologyhydrogel in ophthalmology |
| spellingShingle | Antonio Maria Fea Cristina Novarese Paolo Caselgrandi Giacomo Boscia Glaucoma Treatment and Hydrogel: Current Insights and State of the Art Gels hydrogel drug delivery glaucoma nanoparticles ophthalmology hydrogel in ophthalmology |
| title | Glaucoma Treatment and Hydrogel: Current Insights and State of the Art |
| title_full | Glaucoma Treatment and Hydrogel: Current Insights and State of the Art |
| title_fullStr | Glaucoma Treatment and Hydrogel: Current Insights and State of the Art |
| title_full_unstemmed | Glaucoma Treatment and Hydrogel: Current Insights and State of the Art |
| title_short | Glaucoma Treatment and Hydrogel: Current Insights and State of the Art |
| title_sort | glaucoma treatment and hydrogel current insights and state of the art |
| topic | hydrogel drug delivery glaucoma nanoparticles ophthalmology hydrogel in ophthalmology |
| url | https://www.mdpi.com/2310-2861/8/8/510 |
| work_keys_str_mv | AT antoniomariafea glaucomatreatmentandhydrogelcurrentinsightsandstateoftheart AT cristinanovarese glaucomatreatmentandhydrogelcurrentinsightsandstateoftheart AT paolocaselgrandi glaucomatreatmentandhydrogelcurrentinsightsandstateoftheart AT giacomoboscia glaucomatreatmentandhydrogelcurrentinsightsandstateoftheart |