Differential diagnosis of the epileptogenic supratentorial brain tumors in children
Fifty-six out of 79 pediatric patients with supratentorial brain tumors were noted to have symptomatic epilepsy. Dysembryoplastic neuroepithelial tumors (DNET), diffuse astrocytomas (DA), and gangliogliomas (GG) were the most epileptogenic tumors. Seizures were new-onset in all our noted cases of DN...
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2016-03-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/164 |
| _version_ | 1797875284386512896 |
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| author | V. S. Khalilov A. A. Kholin N. A. Medvedeva I. G. Vasiliev I. V. Rasskazchikova A. N. Kislyakov R. R. Ismailova N. N. Zavadenko |
| author_facet | V. S. Khalilov A. A. Kholin N. A. Medvedeva I. G. Vasiliev I. V. Rasskazchikova A. N. Kislyakov R. R. Ismailova N. N. Zavadenko |
| author_sort | V. S. Khalilov |
| collection | DOAJ |
| description | Fifty-six out of 79 pediatric patients with supratentorial brain tumors were noted to have symptomatic epilepsy. Dysembryoplastic neuroepithelial tumors (DNET), diffuse astrocytomas (DA), and gangliogliomas (GG) were the most epileptogenic tumors. Seizures were new-onset in all our noted cases of DNET and in 4 patients with GG and the only clinical tumor sign in 6 of 8 cases of DNET. The neuroimaging features of the MRI pattern of DNET, DA, and GG were an iso/hypointense signal on Tl-weighted magnetic resonance images and a signal, the intensity of which varied from heterogeneous to cerebrospinal fluid, on T2-weighted FLAIR images. Cases of DNET and GG displayed no mass effect or perifocal edema, a trend towards location in the temporoinsular regions, and a frequent concurrence with local gray-white matter differentiation disorders and atrophy. The FLAIR images clearly showed the so-called foam-like (multicystic) structure with pericystic changes. No significant change in the dimensions of the identified DNET and GG was observed during the follow up period. In low-grade DA, tumor growth was reduced and it is difficult to differentiate minimal perifocal edema from tumor-like tissue. The sensitivity of these tumors to contrast enhancement is ambiguous. Along with DNET (that was epileptogenic in 100% of cases), DA (91,7%) and GG (80%) were the most common epileptogenic brain tumors. |
| first_indexed | 2024-04-10T01:45:11Z |
| format | Article |
| id | doaj.art-0775b29414144bd9a586be6f154900ac |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:45:11Z |
| publishDate | 2016-03-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-0775b29414144bd9a586be6f154900ac2023-03-13T09:12:41ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282016-03-01605103112157Differential diagnosis of the epileptogenic supratentorial brain tumors in childrenV. S. Khalilov0A. A. Kholin1N. A. Medvedeva2I. G. Vasiliev3I. V. Rasskazchikova4A. N. Kislyakov5R. R. Ismailova6N. N. Zavadenko7ФГБУЗ «Центральная детская клиническая больница» ФМБА России; РНИМУ им. Н.И. Пирогова Минздрава РФ; Российская детская клиническая больница Минздрава РФ; ФГБУ «Морозовская детская городская клиническая больница» Департамента здравоохранения МосквыФГБУЗ «Центральная детская клиническая больница» ФМБА России; РНИМУ им. Н.И. Пирогова Минздрава РФ; Российская детская клиническая больница Минздрава РФ; ФГБУ «Морозовская детская городская клиническая больница» Департамента здравоохранения МосквыФГБУЗ «Центральная детская клиническая больница» ФМБА России; РНИМУ им. Н.И. Пирогова Минздрава РФ; Российская детская клиническая больница Минздрава РФ; ФГБУ «Морозовская детская городская клиническая больница» Департамента здравоохранения МосквыФГБУЗ «Центральная детская клиническая больница» ФМБА России; РНИМУ им. Н.И. Пирогова Минздрава РФ; Российская детская клиническая больница Минздрава РФ; ФГБУ «Морозовская детская городская клиническая больница» Департамента здравоохранения МосквыФГБУЗ «Центральная детская клиническая больница» ФМБА России; РНИМУ им. Н.И. Пирогова Минздрава РФ; Российская детская клиническая больница Минздрава РФ; ФГБУ «Морозовская детская городская клиническая больница» Департамента здравоохранения МосквыФГБУЗ «Центральная детская клиническая больница» ФМБА России; РНИМУ им. Н.И. Пирогова Минздрава РФ; Российская детская клиническая больница Минздрава РФ; ФГБУ «Морозовская детская городская клиническая больница» Департамента здравоохранения МосквыФГБУЗ «Центральная детская клиническая больница» ФМБА России; РНИМУ им. Н.И. Пирогова Минздрава РФ; Российская детская клиническая больница Минздрава РФ; ФГБУ «Морозовская детская городская клиническая больница» Департамента здравоохранения МосквыФГБУЗ «Центральная детская клиническая больница» ФМБА России; РНИМУ им. Н.И. Пирогова Минздрава РФ; Российская детская клиническая больница Минздрава РФ; ФГБУ «Морозовская детская городская клиническая больница» Департамента здравоохранения МосквыFifty-six out of 79 pediatric patients with supratentorial brain tumors were noted to have symptomatic epilepsy. Dysembryoplastic neuroepithelial tumors (DNET), diffuse astrocytomas (DA), and gangliogliomas (GG) were the most epileptogenic tumors. Seizures were new-onset in all our noted cases of DNET and in 4 patients with GG and the only clinical tumor sign in 6 of 8 cases of DNET. The neuroimaging features of the MRI pattern of DNET, DA, and GG were an iso/hypointense signal on Tl-weighted magnetic resonance images and a signal, the intensity of which varied from heterogeneous to cerebrospinal fluid, on T2-weighted FLAIR images. Cases of DNET and GG displayed no mass effect or perifocal edema, a trend towards location in the temporoinsular regions, and a frequent concurrence with local gray-white matter differentiation disorders and atrophy. The FLAIR images clearly showed the so-called foam-like (multicystic) structure with pericystic changes. No significant change in the dimensions of the identified DNET and GG was observed during the follow up period. In low-grade DA, tumor growth was reduced and it is difficult to differentiate minimal perifocal edema from tumor-like tissue. The sensitivity of these tumors to contrast enhancement is ambiguous. Along with DNET (that was epileptogenic in 100% of cases), DA (91,7%) and GG (80%) were the most common epileptogenic brain tumors.https://www.ped-perinatology.ru/jour/article/view/164опухоли головного мозгасимптоматическая фокальная эпилепсиянейровизуализация. |
| spellingShingle | V. S. Khalilov A. A. Kholin N. A. Medvedeva I. G. Vasiliev I. V. Rasskazchikova A. N. Kislyakov R. R. Ismailova N. N. Zavadenko Differential diagnosis of the epileptogenic supratentorial brain tumors in children Rossijskij Vestnik Perinatologii i Pediatrii опухоли головного мозга симптоматическая фокальная эпилепсия нейровизуализация. |
| title | Differential diagnosis of the epileptogenic supratentorial brain tumors in children |
| title_full | Differential diagnosis of the epileptogenic supratentorial brain tumors in children |
| title_fullStr | Differential diagnosis of the epileptogenic supratentorial brain tumors in children |
| title_full_unstemmed | Differential diagnosis of the epileptogenic supratentorial brain tumors in children |
| title_short | Differential diagnosis of the epileptogenic supratentorial brain tumors in children |
| title_sort | differential diagnosis of the epileptogenic supratentorial brain tumors in children |
| topic | опухоли головного мозга симптоматическая фокальная эпилепсия нейровизуализация. |
| url | https://www.ped-perinatology.ru/jour/article/view/164 |
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