Spontaneous Intracerebral Hemorrhage: Management
Spontaneous non-traumatic intracerebral hemorrhage (ICH) remains a significant cause of mortality and morbidity throughout the world. To improve the devastating course of ICH, various clinical trials for medical and surgical interventions have been conducted in the last 10 years. Recent large-scale...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Korean Stroke Society
2017-01-01
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| Series: | Journal of Stroke |
| Subjects: | |
| Online Access: | http://www.j-stroke.org/upload/pdf/jos-2016-01935.pdf |
| _version_ | 1819172484848549888 |
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| author | Jun Yup Kim Hee-Joon Bae |
| author_facet | Jun Yup Kim Hee-Joon Bae |
| author_sort | Jun Yup Kim |
| collection | DOAJ |
| description | Spontaneous non-traumatic intracerebral hemorrhage (ICH) remains a significant cause of mortality and morbidity throughout the world. To improve the devastating course of ICH, various clinical trials for medical and surgical interventions have been conducted in the last 10 years. Recent large-scale clinical trials have reported that early intensive blood pressure reduction can be a safe and feasible strategy for ICH, and have suggested a safe target range for systolic blood pressure. While new medical therapies associated with warfarin and non-vitamin K antagonist oral anticoagulants have been developed to treat ICH, recent trials have not been able to demonstrate the overall beneficial effects of surgical intervention on mortality and functional outcomes. However, some patients with ICH may benefit from surgical management in specific clinical contexts and/or at specific times. Furthermore, clinical trials for minimally invasive surgical evacuation methods are ongoing and may provide positive evidence. Upon understanding the current guidelines for the management of ICH, clinicians can administer appropriate treatment and attempt to improve the clinical outcome of ICH. The purpose of this review is to help in the decision-making of the medical and surgical management of ICH. |
| first_indexed | 2024-12-22T20:07:55Z |
| format | Article |
| id | doaj.art-07769f92ed4d400cb22fe714513f9954 |
| institution | Directory Open Access Journal |
| issn | 2287-6391 2287-6405 |
| language | English |
| last_indexed | 2024-12-22T20:07:55Z |
| publishDate | 2017-01-01 |
| publisher | Korean Stroke Society |
| record_format | Article |
| series | Journal of Stroke |
| spelling | doaj.art-07769f92ed4d400cb22fe714513f99542022-12-21T18:14:06ZengKorean Stroke SocietyJournal of Stroke2287-63912287-64052017-01-01191283910.5853/jos.2016.01935164Spontaneous Intracerebral Hemorrhage: ManagementJun Yup KimHee-Joon BaeSpontaneous non-traumatic intracerebral hemorrhage (ICH) remains a significant cause of mortality and morbidity throughout the world. To improve the devastating course of ICH, various clinical trials for medical and surgical interventions have been conducted in the last 10 years. Recent large-scale clinical trials have reported that early intensive blood pressure reduction can be a safe and feasible strategy for ICH, and have suggested a safe target range for systolic blood pressure. While new medical therapies associated with warfarin and non-vitamin K antagonist oral anticoagulants have been developed to treat ICH, recent trials have not been able to demonstrate the overall beneficial effects of surgical intervention on mortality and functional outcomes. However, some patients with ICH may benefit from surgical management in specific clinical contexts and/or at specific times. Furthermore, clinical trials for minimally invasive surgical evacuation methods are ongoing and may provide positive evidence. Upon understanding the current guidelines for the management of ICH, clinicians can administer appropriate treatment and attempt to improve the clinical outcome of ICH. The purpose of this review is to help in the decision-making of the medical and surgical management of ICH.http://www.j-stroke.org/upload/pdf/jos-2016-01935.pdfstrokecerebrovascular disordersintracranial hemorrhagescerebral hemorrhagetherapeutics |
| spellingShingle | Jun Yup Kim Hee-Joon Bae Spontaneous Intracerebral Hemorrhage: Management Journal of Stroke stroke cerebrovascular disorders intracranial hemorrhages cerebral hemorrhage therapeutics |
| title | Spontaneous Intracerebral Hemorrhage: Management |
| title_full | Spontaneous Intracerebral Hemorrhage: Management |
| title_fullStr | Spontaneous Intracerebral Hemorrhage: Management |
| title_full_unstemmed | Spontaneous Intracerebral Hemorrhage: Management |
| title_short | Spontaneous Intracerebral Hemorrhage: Management |
| title_sort | spontaneous intracerebral hemorrhage management |
| topic | stroke cerebrovascular disorders intracranial hemorrhages cerebral hemorrhage therapeutics |
| url | http://www.j-stroke.org/upload/pdf/jos-2016-01935.pdf |
| work_keys_str_mv | AT junyupkim spontaneousintracerebralhemorrhagemanagement AT heejoonbae spontaneousintracerebralhemorrhagemanagement |