Transcriptomic analysis and mutational status of IDH1 in paired primary-recurrent intrahepatic cholangiocarcinoma

Transcriptomic analysis and mutational status of IDH1 in paired primary-recurrent intrahepatic cholangiocarcinoma

Abstract Background Effective target therapies for intrahepatic cholangiocarcinoma (ICC) have not been identified so far. One of the reasons may be the genetic evolution from primary (PR) to recurrent (REC) tumors. We aim to identify peculiar characteristics and to select potential targets specific...

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Bibliographic Details
Main Authors: C. Peraldo-Neia, P. Ostano, G. Cavalloni, Y. Pignochino, D. Sangiolo, L. De Cecco, E. Marchesi, D. Ribero, A. Scarpa, A. M. De Rose, A. Giuliani, F. Calise, C. Raggi, P. Invernizzi, M. Aglietta, G. Chiorino, F. Leone
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Genomics
Subjects:
Intrahepatic cholangiocarcinoma
Recurrence
IDH1 mutation
Microarray
Prognostic marker
Online Access:http://link.springer.com/article/10.1186/s12864-018-4829-0

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