Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after Exercise
High-strength or long-duration exercise can lead to significant fatigue, oxidative stress, and muscle damage. The purpose of this study was to examine the effect of mangosteen concentrate drink (MCD) supplementation on antioxidant capacity and lactate clearance in rats after running exercise. Forty...
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MDPI AG
2020-05-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/5/1447 |
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| author | Ching-Chien Chang Chia-Wen Chen Eddy Owaga Wan-Ting Lee Ting-Ni Liu Rong-Hong Hsieh |
| author_facet | Ching-Chien Chang Chia-Wen Chen Eddy Owaga Wan-Ting Lee Ting-Ni Liu Rong-Hong Hsieh |
| author_sort | Ching-Chien Chang |
| collection | DOAJ |
| description | High-strength or long-duration exercise can lead to significant fatigue, oxidative stress, and muscle damage. The purpose of this study was to examine the effect of mangosteen concentrate drink (MCD) supplementation on antioxidant capacity and lactate clearance in rats after running exercise. Forty rats were divided into five groups: N, non-treatment; C, control; or supplemented with MCD, including M1, M5, and M10 (0.9, 4.5, and 9 mL/day) for 6 weeks. The rats were subjected to 30 min running and exhaustive-running tests using a treadmill. The blood lactate; triglyceride; cholesterol and glucose levels; hepatic and muscular malonaldehyde (MDA) levels; and antioxidant enzymes, including superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT), were analyzed. The results of this study demonstrated that MCD supplementation can increase GPx and CAT activities, alleviate oxidative stress in muscle, and increase lactate clearance, and is thereby beneficial to reduced muscle fatigue after exercise. |
| first_indexed | 2024-03-10T19:46:18Z |
| format | Article |
| id | doaj.art-0776f62acd054ada8d364076051a893a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T19:46:18Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-0776f62acd054ada8d364076051a893a2023-11-20T00:44:51ZengMDPI AGNutrients2072-66432020-05-01125144710.3390/nu12051447Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after ExerciseChing-Chien Chang0Chia-Wen Chen1Eddy Owaga2Wan-Ting Lee3Ting-Ni Liu4Rong-Hong Hsieh5School of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, TaiwanSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, TaiwanInstitute of Food Bioresources Technology, Dedan Kimathi University of Technology, Nyeri 10100, KenyaSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, TaiwanSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, TaiwanSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, TaiwanHigh-strength or long-duration exercise can lead to significant fatigue, oxidative stress, and muscle damage. The purpose of this study was to examine the effect of mangosteen concentrate drink (MCD) supplementation on antioxidant capacity and lactate clearance in rats after running exercise. Forty rats were divided into five groups: N, non-treatment; C, control; or supplemented with MCD, including M1, M5, and M10 (0.9, 4.5, and 9 mL/day) for 6 weeks. The rats were subjected to 30 min running and exhaustive-running tests using a treadmill. The blood lactate; triglyceride; cholesterol and glucose levels; hepatic and muscular malonaldehyde (MDA) levels; and antioxidant enzymes, including superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT), were analyzed. The results of this study demonstrated that MCD supplementation can increase GPx and CAT activities, alleviate oxidative stress in muscle, and increase lactate clearance, and is thereby beneficial to reduced muscle fatigue after exercise.https://www.mdpi.com/2072-6643/12/5/1447antioxidant capacityexerciselactate clearancemangosteenoxidative stress |
| spellingShingle | Ching-Chien Chang Chia-Wen Chen Eddy Owaga Wan-Ting Lee Ting-Ni Liu Rong-Hong Hsieh Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after Exercise Nutrients antioxidant capacity exercise lactate clearance mangosteen oxidative stress |
| title | Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after Exercise |
| title_full | Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after Exercise |
| title_fullStr | Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after Exercise |
| title_full_unstemmed | Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after Exercise |
| title_short | Mangosteen Concentrate Drink Supplementation Promotes Antioxidant Status and Lactate Clearance in Rats after Exercise |
| title_sort | mangosteen concentrate drink supplementation promotes antioxidant status and lactate clearance in rats after exercise |
| topic | antioxidant capacity exercise lactate clearance mangosteen oxidative stress |
| url | https://www.mdpi.com/2072-6643/12/5/1447 |
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