Drug metabolite cluster centers-based strategy for comprehensive profiling of Neomangiferin metabolites in vivo and in vitro and network pharmacology study on anti-inflammatory mechanism

Drug metabolite cluster centers-based strategy for comprehensive profiling of Neomangiferin metabolites in vivo and in vitro and network pharmacology study on anti-inflammatory mechanism

Neomangiferin (NMF) is an extremely special xanthone that could be simultaneously attributed to C-glycoside and O-glycoside with a variety of biological activities, such as anti-inflammatory, antitumor, antipyretic, and so on. So far as we know, the metabolism profiling has been insufficient until n...

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Bibliographic Details
Main Authors: Xianming Lan, Yanan Li, Haoran Li, Shuyi Song, Xiaoqing Yuan, Hongyan Zhou, Qimei Chen, Jiayu Zhang
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Arabian Journal of Chemistry
Subjects:
Drug Metabolism Cluster Centers-based strategy
Neomangiferin
UHPLC-Q-Exactive Orbitrap MS
Anti-inflammatory
Network pharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222005846

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