Characterisation of Hyaluronic Acid Blends Modified by Poly(<i>N</i>-Vinylpyrrolidone)
The viscosity behaviour and physical properties of blends containing hyaluronic acid (HA) and poly(<i>N</i>-vinylpyrrolidone) (PVP) were studied by the viscometric technique, steady shear tests, tensile tests and infrared spectroscopy. Viscometric and rheological measurements were carrie...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/17/5233 |
| _version_ | 1797521003342987264 |
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| author | Katarzyna Lewandowska Marta Szulc |
| author_facet | Katarzyna Lewandowska Marta Szulc |
| author_sort | Katarzyna Lewandowska |
| collection | DOAJ |
| description | The viscosity behaviour and physical properties of blends containing hyaluronic acid (HA) and poly(<i>N</i>-vinylpyrrolidone) (PVP) were studied by the viscometric technique, steady shear tests, tensile tests and infrared spectroscopy. Viscometric and rheological measurements were carried out using blends of HA/PVP with different HA weight fractions (0, 0.2, 0.5, 0.8 and 1). The polymer films and HA/PVP blend films were prepared using the solution casting method. The study of HA blends by viscometry showed that HA/PVP was miscible with the exception of the blend with high HA content. HA and its blends showed a shear-thinning flow behaviour. The non-Newtonian indices (<i>n</i>) of HA/PVP blends were calculated by the Ostwald–de Waele equation, indicating a shear-thinning effect in which pseudoplasticity increased with increasing HA contents. Mechanical properties, such as tensile strength and elongation at the break, were higher for HA/PVP films with w<sub>HA</sub> = 0.5 compared to those with higher HA contents. The elongation at the break of HA/PVP blend films displayed a pronounced increase compared to HA films. Moreover, infrared analysis confirmed the existence of interactions between HA and PVP. The blending of HA with PVP generated films with elasticity and better properties than homopolymer films. |
| first_indexed | 2024-03-10T08:06:30Z |
| format | Article |
| id | doaj.art-077da8e3364949d0a256ece1314ef716 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T08:06:30Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-077da8e3364949d0a256ece1314ef7162023-11-22T11:01:06ZengMDPI AGMolecules1420-30492021-08-012617523310.3390/molecules26175233Characterisation of Hyaluronic Acid Blends Modified by Poly(<i>N</i>-Vinylpyrrolidone)Katarzyna Lewandowska0Marta Szulc1Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7, 87-100 Toruń, PolandFaculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7, 87-100 Toruń, PolandThe viscosity behaviour and physical properties of blends containing hyaluronic acid (HA) and poly(<i>N</i>-vinylpyrrolidone) (PVP) were studied by the viscometric technique, steady shear tests, tensile tests and infrared spectroscopy. Viscometric and rheological measurements were carried out using blends of HA/PVP with different HA weight fractions (0, 0.2, 0.5, 0.8 and 1). The polymer films and HA/PVP blend films were prepared using the solution casting method. The study of HA blends by viscometry showed that HA/PVP was miscible with the exception of the blend with high HA content. HA and its blends showed a shear-thinning flow behaviour. The non-Newtonian indices (<i>n</i>) of HA/PVP blends were calculated by the Ostwald–de Waele equation, indicating a shear-thinning effect in which pseudoplasticity increased with increasing HA contents. Mechanical properties, such as tensile strength and elongation at the break, were higher for HA/PVP films with w<sub>HA</sub> = 0.5 compared to those with higher HA contents. The elongation at the break of HA/PVP blend films displayed a pronounced increase compared to HA films. Moreover, infrared analysis confirmed the existence of interactions between HA and PVP. The blending of HA with PVP generated films with elasticity and better properties than homopolymer films.https://www.mdpi.com/1420-3049/26/17/5233polymer blendsrheological propertiespoly(<i>N</i>-vinylpyrrolidone)hyaluronic acid |
| spellingShingle | Katarzyna Lewandowska Marta Szulc Characterisation of Hyaluronic Acid Blends Modified by Poly(<i>N</i>-Vinylpyrrolidone) Molecules polymer blends rheological properties poly(<i>N</i>-vinylpyrrolidone) hyaluronic acid |
| title | Characterisation of Hyaluronic Acid Blends Modified by Poly(<i>N</i>-Vinylpyrrolidone) |
| title_full | Characterisation of Hyaluronic Acid Blends Modified by Poly(<i>N</i>-Vinylpyrrolidone) |
| title_fullStr | Characterisation of Hyaluronic Acid Blends Modified by Poly(<i>N</i>-Vinylpyrrolidone) |
| title_full_unstemmed | Characterisation of Hyaluronic Acid Blends Modified by Poly(<i>N</i>-Vinylpyrrolidone) |
| title_short | Characterisation of Hyaluronic Acid Blends Modified by Poly(<i>N</i>-Vinylpyrrolidone) |
| title_sort | characterisation of hyaluronic acid blends modified by poly i n i vinylpyrrolidone |
| topic | polymer blends rheological properties poly(<i>N</i>-vinylpyrrolidone) hyaluronic acid |
| url | https://www.mdpi.com/1420-3049/26/17/5233 |
| work_keys_str_mv | AT katarzynalewandowska characterisationofhyaluronicacidblendsmodifiedbypolyinivinylpyrrolidone AT martaszulc characterisationofhyaluronicacidblendsmodifiedbypolyinivinylpyrrolidone |