Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions
<p>Abstract</p> <p>Background</p> <p>Neurological abnormalities have been reported in people with amnestic mild cognitive impairment (aMCI). The current study aimed to examine the prevalence of neurological soft signs (NSS) in this clinical group and to examine the rela...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2012-06-01
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| Series: | Behavioral and Brain Functions |
| Subjects: | |
| Online Access: | http://www.behavioralandbrainfunctions.com/content/8/1/29 |
| _version_ | 1818682452753776640 |
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| author | Li Hui-jie Wang Peng-yun Jiang Yang Chan Raymond C K Wang Hua-li Li Juan |
| author_facet | Li Hui-jie Wang Peng-yun Jiang Yang Chan Raymond C K Wang Hua-li Li Juan |
| author_sort | Li Hui-jie |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Neurological abnormalities have been reported in people with amnestic mild cognitive impairment (aMCI). The current study aimed to examine the prevalence of neurological soft signs (NSS) in this clinical group and to examine the relationship of NSS to other neuropsychological performances.</p> <p>Methods</p> <p>Twenty-nine people with aMCI and 28 cognitively healthy elderly people were recruited for the present study. The NSS subscales (motor coordination, sensory integration, and disinhibition) of the Cambridge Neurological Inventory and a set of neuropsychological tests were administered to all the participants.</p> <p>Results</p> <p>People with aMCI exhibited significantly more motor coordination signs, disinhibition signs, and total NSS than normal controls. Correlation analysis showed that the motor coordination subscale score and total score of NSS were significantly inversely correlated with the combined Z-score of neuropsychological tests in aMCI group.</p> <p>Conclusions</p> <p>These preliminary findings suggested that people with aMCI demonstrated a higher prevalence of NSS compared to healthy elderly people. Moreover, NSS was found to be inversely correlated with the neuropsychological performances in persons with aMCI. When taken together, these findings suggested that NSS may play a potential important role and serve as a tool to assist in the early detection of aMCI.</p> |
| first_indexed | 2024-12-17T10:19:04Z |
| format | Article |
| id | doaj.art-077fd58a4d62495d919e5117a129264a |
| institution | Directory Open Access Journal |
| issn | 1744-9081 |
| language | English |
| last_indexed | 2024-12-17T10:19:04Z |
| publishDate | 2012-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Behavioral and Brain Functions |
| spelling | doaj.art-077fd58a4d62495d919e5117a129264a2022-12-21T21:52:51ZengBMCBehavioral and Brain Functions1744-90812012-06-01812910.1186/1744-9081-8-29Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functionsLi Hui-jieWang Peng-yunJiang YangChan Raymond C KWang Hua-liLi Juan<p>Abstract</p> <p>Background</p> <p>Neurological abnormalities have been reported in people with amnestic mild cognitive impairment (aMCI). The current study aimed to examine the prevalence of neurological soft signs (NSS) in this clinical group and to examine the relationship of NSS to other neuropsychological performances.</p> <p>Methods</p> <p>Twenty-nine people with aMCI and 28 cognitively healthy elderly people were recruited for the present study. The NSS subscales (motor coordination, sensory integration, and disinhibition) of the Cambridge Neurological Inventory and a set of neuropsychological tests were administered to all the participants.</p> <p>Results</p> <p>People with aMCI exhibited significantly more motor coordination signs, disinhibition signs, and total NSS than normal controls. Correlation analysis showed that the motor coordination subscale score and total score of NSS were significantly inversely correlated with the combined Z-score of neuropsychological tests in aMCI group.</p> <p>Conclusions</p> <p>These preliminary findings suggested that people with aMCI demonstrated a higher prevalence of NSS compared to healthy elderly people. Moreover, NSS was found to be inversely correlated with the neuropsychological performances in persons with aMCI. When taken together, these findings suggested that NSS may play a potential important role and serve as a tool to assist in the early detection of aMCI.</p>http://www.behavioralandbrainfunctions.com/content/8/1/29Mild cognitive impairmentNeurological soft signsNeuropsychological tests |
| spellingShingle | Li Hui-jie Wang Peng-yun Jiang Yang Chan Raymond C K Wang Hua-li Li Juan Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions Behavioral and Brain Functions Mild cognitive impairment Neurological soft signs Neuropsychological tests |
| title | Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions |
| title_full | Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions |
| title_fullStr | Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions |
| title_full_unstemmed | Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions |
| title_short | Neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions |
| title_sort | neurological soft signs in persons with amnestic mild cognitive impairment and the relationships to neuropsychological functions |
| topic | Mild cognitive impairment Neurological soft signs Neuropsychological tests |
| url | http://www.behavioralandbrainfunctions.com/content/8/1/29 |
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