Brain cells in the avian 'prefrontal cortex' code for features of slot-machine-like gambling.
Slot machines are the most common and addictive form of gambling. In the current study, we recorded from single neurons in the 'prefrontal cortex' of pigeons while they played a slot-machine-like task. We identified four categories of neurons that coded for different aspects of our slot-ma...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283622/?tool=EBI |
| _version_ | 1818735367447117824 |
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| author | Damian Scarf Kirby Miles Amanda Sloan Natalie Goulter Matt Hegan Azade Seid-Fatemi David Harper Michael Colombo |
| author_facet | Damian Scarf Kirby Miles Amanda Sloan Natalie Goulter Matt Hegan Azade Seid-Fatemi David Harper Michael Colombo |
| author_sort | Damian Scarf |
| collection | DOAJ |
| description | Slot machines are the most common and addictive form of gambling. In the current study, we recorded from single neurons in the 'prefrontal cortex' of pigeons while they played a slot-machine-like task. We identified four categories of neurons that coded for different aspects of our slot-machine-like task. Reward-Proximity neurons showed a linear increase in activity as the opportunity for a reward drew near. I-Won neurons fired only when the fourth stimulus of a winning (four-of-a-kind) combination was displayed. I-Lost neurons changed their firing rate at the presentation of the first nonidentical stimulus, that is, when it was apparent that no reward was forthcoming. Finally, Near-Miss neurons also changed their activity the moment it was recognized that a reward was no longer available, but more importantly, the activity level was related to whether the trial contained one, two, or three identical stimuli prior to the display of the nonidentical stimulus. These findings not only add to recent neurophysiological research employing simulated gambling paradigms, but also add to research addressing the functional correspondence between the avian NCL and primate PFC. |
| first_indexed | 2024-12-18T00:20:08Z |
| format | Article |
| id | doaj.art-078080df321f43e08b965c6a8753091d |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-18T00:20:08Z |
| publishDate | 2011-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-078080df321f43e08b965c6a8753091d2022-12-21T21:27:20ZengPublic Library of Science (PLoS)PLoS ONE1932-62032011-01-0161e1458910.1371/journal.pone.0014589Brain cells in the avian 'prefrontal cortex' code for features of slot-machine-like gambling.Damian ScarfKirby MilesAmanda SloanNatalie GoulterMatt HeganAzade Seid-FatemiDavid HarperMichael ColomboSlot machines are the most common and addictive form of gambling. In the current study, we recorded from single neurons in the 'prefrontal cortex' of pigeons while they played a slot-machine-like task. We identified four categories of neurons that coded for different aspects of our slot-machine-like task. Reward-Proximity neurons showed a linear increase in activity as the opportunity for a reward drew near. I-Won neurons fired only when the fourth stimulus of a winning (four-of-a-kind) combination was displayed. I-Lost neurons changed their firing rate at the presentation of the first nonidentical stimulus, that is, when it was apparent that no reward was forthcoming. Finally, Near-Miss neurons also changed their activity the moment it was recognized that a reward was no longer available, but more importantly, the activity level was related to whether the trial contained one, two, or three identical stimuli prior to the display of the nonidentical stimulus. These findings not only add to recent neurophysiological research employing simulated gambling paradigms, but also add to research addressing the functional correspondence between the avian NCL and primate PFC.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283622/?tool=EBI |
| spellingShingle | Damian Scarf Kirby Miles Amanda Sloan Natalie Goulter Matt Hegan Azade Seid-Fatemi David Harper Michael Colombo Brain cells in the avian 'prefrontal cortex' code for features of slot-machine-like gambling. PLoS ONE |
| title | Brain cells in the avian 'prefrontal cortex' code for features of slot-machine-like gambling. |
| title_full | Brain cells in the avian 'prefrontal cortex' code for features of slot-machine-like gambling. |
| title_fullStr | Brain cells in the avian 'prefrontal cortex' code for features of slot-machine-like gambling. |
| title_full_unstemmed | Brain cells in the avian 'prefrontal cortex' code for features of slot-machine-like gambling. |
| title_short | Brain cells in the avian 'prefrontal cortex' code for features of slot-machine-like gambling. |
| title_sort | brain cells in the avian prefrontal cortex code for features of slot machine like gambling |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283622/?tool=EBI |
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