Aberrant BMP2 Signaling in Patients Diagnosed with Osteoporosis

Aberrant BMP2 Signaling in Patients Diagnosed with Osteoporosis

The most common bone disease in humans is osteoporosis (OP). Current therapeutics targeting OP have several negative side effects. Bone morphogenetic protein 2 (BMP2) is a potent growth factor that is known to activate both osteoblasts and osteoclasts. It completes these actions through both SMAD-de...

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Bibliographic Details
Main Authors: Hilary W. Durbano, Daniel Halloran, John Nguyen, Victoria Stone, Sean McTague, Mark Eskander, Anja Nohe
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
osteoporosis
BMP2
CK2.3
BMPRIa
CK2
Online Access:https://www.mdpi.com/1422-0067/21/18/6909

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