Genotoxins: The Mechanistic Links between <i>Escherichia coli</i> and Colorectal Cancer
Emerging evidence indicates bacterial infections contribute to the formation of cancers. Bacterial genotoxins are effectors that cause DNA damage by introducing single- and double-strand DNA breaks in the host cells. The first bacterial genotoxin cytolethal distending toxin (CDT) was a protein ident...
Main Authors: | Ya Wang, Kai Fu |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/15/4/1152 |
Similar Items
-
Escherichia coli from biopsies differ in virulence genes between patients with colorectal neoplasia and healthy controls
by: Juraj Bosák, et al.
Published: (2023-04-01) -
Shining a Light on Colibactin Biology
by: Michael W. Dougherty, et al.
Published: (2021-05-01) -
Bacterial Genotoxin-Induced DNA Damage and Modulation of the Host Immune Microenvironment
by: Océane C.B. Martin, et al.
Published: (2020-01-01) -
Bacterial genotoxin functions as immune-modulator and promotes host survival
by: Riccardo Guidi, et al.
Published: (2016-07-01) -
Bacterial Genotoxins: Merging the DNA Damage Response into Infection Biology
by: Francesca Grasso, et al.
Published: (2015-08-01)