Genetic Analysis of Patients with Congenital Hypogonadotropic Hypogonadism: A Case Series

Genetic Analysis of Patients with Congenital Hypogonadotropic Hypogonadism: A Case Series

Congenital hypogonadotropic hypogonadism (cHH)/Kallmann syndrome (KS) is a rare genetic disorder with variable penetrance and a complex inheritance pattern. Consequently, it does not always follow Mendelian laws. More recently, digenic and oligogenic transmission has been recognized in 1.5–15% of ca...

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Bibliographic Details
Main Authors: Rossella Cannarella, Carmelo Gusmano, Rosita A. Condorelli, Andrea Bernini, Jurgen Kaftalli, Paolo Enrico Maltese, Stefano Paolacci, Astrit Dautaj, Giuseppe Marceddu, Matteo Bertelli, Sandro La Vignera, Aldo E. Calogero
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
hypogonadotropic hypogonadism
Kallmann syndrome
amino acid conservation
molecular modeling
Online Access:https://www.mdpi.com/1422-0067/24/8/7428

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