Tobacco and Nervous System Development and Function—New Findings 2015–2020
Tobacco is a one of the most common addictive stimulants used by people around the world. The smoke generated during tobacco combustion is a toxic mixture of more than 5000 chemicals of which over 30 are known human carcinogens. While its negative effects on the human body are well understood, it re...
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MDPI AG
2021-06-01
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author | Wojciech Hajdusianek Aleksandra Żórawik Marta Waliszewska-Prosół Rafał Poręba Paweł Gać |
author_facet | Wojciech Hajdusianek Aleksandra Żórawik Marta Waliszewska-Prosół Rafał Poręba Paweł Gać |
author_sort | Wojciech Hajdusianek |
collection | DOAJ |
description | Tobacco is a one of the most common addictive stimulants used by people around the world. The smoke generated during tobacco combustion is a toxic mixture of more than 5000 chemicals of which over 30 are known human carcinogens. While its negative effects on the human body are well understood, it remains a serious public health problem. One of the multiple effects of smoking is tobacco’s effect on the nervous system—its development and function. This review aims to summarize the progress made in research on the effects of tobacco on the nervous system both of the perinatal period and adults and both in animals and humans in 2015–2020. The 1245 results that corresponded to the keywords “tobacco, cigarette, nervous system, brain, morphology, function” were reviewed, of which 200 abstracts were considered significant. Most of those articles broadened the knowledge about the negative effects of smoking on the human nervous system. Tobacco has a significant negative impact on the development of nervous structures, neurotransmission and cognitive functions, and promotes the development of neurodegenerative diseases, insomnia and cerebrovascular diseases. The only exception is the protective effect of the dopaminergic system in Parkinson’s disease. In conclusion, in recent years much effort has been devoted to describing, revealing and uncovering new aspects of tobacco detrimental to human life. The nicotine contained in tobacco smoke affects the human body in a multidimensional way, including a serious impact on the broadly understood neurological health. |
first_indexed | 2024-03-10T10:21:04Z |
format | Article |
id | doaj.art-0786bb7ad1834d5a8279849afe98ebcd |
institution | Directory Open Access Journal |
issn | 2076-3425 |
language | English |
last_indexed | 2024-03-10T10:21:04Z |
publishDate | 2021-06-01 |
publisher | MDPI AG |
record_format | Article |
series | Brain Sciences |
spelling | doaj.art-0786bb7ad1834d5a8279849afe98ebcd2023-11-22T00:25:25ZengMDPI AGBrain Sciences2076-34252021-06-0111679710.3390/brainsci11060797Tobacco and Nervous System Development and Function—New Findings 2015–2020Wojciech Hajdusianek0Aleksandra Żórawik1Marta Waliszewska-Prosół2Rafał Poręba3Paweł Gać4Department of Hygiene, Wroclaw Medical University, 50-345 Wroclaw, PolandDepartment of Hygiene, Wroclaw Medical University, 50-345 Wroclaw, PolandDepartment of Neurology, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, 50-556 Wroclaw, PolandDepartment of Hygiene, Wroclaw Medical University, 50-345 Wroclaw, PolandTobacco is a one of the most common addictive stimulants used by people around the world. The smoke generated during tobacco combustion is a toxic mixture of more than 5000 chemicals of which over 30 are known human carcinogens. While its negative effects on the human body are well understood, it remains a serious public health problem. One of the multiple effects of smoking is tobacco’s effect on the nervous system—its development and function. This review aims to summarize the progress made in research on the effects of tobacco on the nervous system both of the perinatal period and adults and both in animals and humans in 2015–2020. The 1245 results that corresponded to the keywords “tobacco, cigarette, nervous system, brain, morphology, function” were reviewed, of which 200 abstracts were considered significant. Most of those articles broadened the knowledge about the negative effects of smoking on the human nervous system. Tobacco has a significant negative impact on the development of nervous structures, neurotransmission and cognitive functions, and promotes the development of neurodegenerative diseases, insomnia and cerebrovascular diseases. The only exception is the protective effect of the dopaminergic system in Parkinson’s disease. In conclusion, in recent years much effort has been devoted to describing, revealing and uncovering new aspects of tobacco detrimental to human life. The nicotine contained in tobacco smoke affects the human body in a multidimensional way, including a serious impact on the broadly understood neurological health.https://www.mdpi.com/2076-3425/11/6/797environmental tobacco smokenervous systembrain |
spellingShingle | Wojciech Hajdusianek Aleksandra Żórawik Marta Waliszewska-Prosół Rafał Poręba Paweł Gać Tobacco and Nervous System Development and Function—New Findings 2015–2020 Brain Sciences environmental tobacco smoke nervous system brain |
title | Tobacco and Nervous System Development and Function—New Findings 2015–2020 |
title_full | Tobacco and Nervous System Development and Function—New Findings 2015–2020 |
title_fullStr | Tobacco and Nervous System Development and Function—New Findings 2015–2020 |
title_full_unstemmed | Tobacco and Nervous System Development and Function—New Findings 2015–2020 |
title_short | Tobacco and Nervous System Development and Function—New Findings 2015–2020 |
title_sort | tobacco and nervous system development and function new findings 2015 2020 |
topic | environmental tobacco smoke nervous system brain |
url | https://www.mdpi.com/2076-3425/11/6/797 |
work_keys_str_mv | AT wojciechhajdusianek tobaccoandnervoussystemdevelopmentandfunctionnewfindings20152020 AT aleksandrazorawik tobaccoandnervoussystemdevelopmentandfunctionnewfindings20152020 AT martawaliszewskaprosoł tobaccoandnervoussystemdevelopmentandfunctionnewfindings20152020 AT rafałporeba tobaccoandnervoussystemdevelopmentandfunctionnewfindings20152020 AT pawełgac tobaccoandnervoussystemdevelopmentandfunctionnewfindings20152020 |