Characterization of novel CD19-specific VHHs isolated from a camelid immune library by phage display

Characterization of novel CD19-specific VHHs isolated from a camelid immune library by phage display

Abstract Background Monoclonal antibody (mAb)-based immunotherapies have achieved promising outcomes in the treatment of immunological and oncological indications. CD19 is considered one of the most qualified antigens in the treatment of B-cell neoplasms. VHHs (nanobodies) are known for their physic...

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Bibliographic Details
Main Authors: Mahmoud Ganji, Pooria Safarzadeh Kozani, Fatemeh Rahbarizadeh
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Translational Medicine
Subjects:
CD19
Cancer immunotherapy
VHH
Nanobody
mAb
Phage display
Online Access:https://doi.org/10.1186/s12967-023-04524-6

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