First-in-man open clinical trial of a combined rdESAT-6 and rCFP-10 tuberculosis specific skin test reagent.

First-in-man open clinical trial of a combined rdESAT-6 and rCFP-10 tuberculosis specific skin test reagent.

Tuberculin is still the only available skin test reagent for the diagnosis of mycobacterial infection. The product has a remarkable sensitivity, but poor specificity. Previous studies, including two human phase I clinical trials, have indicated that rdESAT-6 has a potential as an improved skin test...

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Bibliographic Details
Main Authors: Winnie Bergstedt, Pernille N Tingskov, Birgit Thierry-Carstensen, Søren T Hoff, Henrik Aggerbeck, Vibeke O Thomsen, Peter Andersen, Aase B Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2892483?pdf=render

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