Risk of Chronic Kidney Disease among Patients Developing Mild Renal Impairment during Tenofovir-Containing Antiretroviral Treatment.

Risk of Chronic Kidney Disease among Patients Developing Mild Renal Impairment during Tenofovir-Containing Antiretroviral Treatment.

BACKGROUND:Tenofovir (TDF) can cause kidney injury through tubular dysfunction, with or without drop of estimated glomerular filtration rate (eGFR). Whether mild eGFR reductions during treatment should be considered a reason for prompt TDF discontinuation, however, remains unclear. METHODS:Patients...

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Bibliographic Details
Main Authors: Giuseppe Lapadula, Davide Paolo Bernasconi, Salvatore Casari, Franco Maggiolo, Roberto Cauda, Massimo Di Pietro, Nicoletta Ladisa, Laura Sighinolfi, Sarah Dal Zoppo, Francesca Sabbatini, Alessandro Soria, Chiara Pezzoli, Annalisa Mondi, Silvia Costarelli, Maria Grazia Valsecchi, Carlo Torti, Andrea Gori, Italian MASTER cohort
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5025011?pdf=render

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