Protective mechanical ventilation in suspected influenza infection

Abstract INTRODUCTION: Patients with acute respiratory failure due to influenza require ventilatory support. However, mechanical ventilation itself can exacerbate lung damage and increase mortality. METHODS: The aim of this study was to describe a feasible and protective ventilation protocol, wi...

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Main Authors: Letícia Brito Mendes Pimenta, Nicole Zanzarini Sanson, Márcia Souza Volpe, Marcelo Britto Passos Amato, Adilha Misson Rua Micheletti, Luciana de Almeida Silva Teixeira
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2020-10-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100662&tlng=en
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author Letícia Brito Mendes Pimenta
Nicole Zanzarini Sanson
Márcia Souza Volpe
Marcelo Britto Passos Amato
Adilha Misson Rua Micheletti
Luciana de Almeida Silva Teixeira
author_facet Letícia Brito Mendes Pimenta
Nicole Zanzarini Sanson
Márcia Souza Volpe
Marcelo Britto Passos Amato
Adilha Misson Rua Micheletti
Luciana de Almeida Silva Teixeira
author_sort Letícia Brito Mendes Pimenta
collection DOAJ
description Abstract INTRODUCTION: Patients with acute respiratory failure due to influenza require ventilatory support. However, mechanical ventilation itself can exacerbate lung damage and increase mortality. METHODS: The aim of this study was to describe a feasible and protective ventilation protocol, with limitation of the tidal volume to ≤6 mL/kg of the predicted weight and a driving pressure ≤15 cmH2O after application of the alveolar recruitment maneuver and PEEP titration. RESULTS: Initial improvement in oxygenation and respiratory mechanics were observed in the four cases submitted to the proposed protocol. CONCLUSIONS: Our results indicate that the mechanical ventilation strategy applied could be optimized.
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spelling doaj.art-078d2eb9c3664e5d81a4c8fabf8377182022-12-22T00:28:50ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492020-10-015310.1590/0037-8682-0481-2019Protective mechanical ventilation in suspected influenza infectionLetícia Brito Mendes Pimentahttps://orcid.org/0000-0001-5802-0184Nicole Zanzarini SansonMárcia Souza VolpeMarcelo Britto Passos AmatoAdilha Misson Rua MichelettiLuciana de Almeida Silva TeixeiraAbstract INTRODUCTION: Patients with acute respiratory failure due to influenza require ventilatory support. However, mechanical ventilation itself can exacerbate lung damage and increase mortality. METHODS: The aim of this study was to describe a feasible and protective ventilation protocol, with limitation of the tidal volume to ≤6 mL/kg of the predicted weight and a driving pressure ≤15 cmH2O after application of the alveolar recruitment maneuver and PEEP titration. RESULTS: Initial improvement in oxygenation and respiratory mechanics were observed in the four cases submitted to the proposed protocol. CONCLUSIONS: Our results indicate that the mechanical ventilation strategy applied could be optimized.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100662&tlng=enAcute respiratory distress syndromeInfluenza virusMechanical ventilation
spellingShingle Letícia Brito Mendes Pimenta
Nicole Zanzarini Sanson
Márcia Souza Volpe
Marcelo Britto Passos Amato
Adilha Misson Rua Micheletti
Luciana de Almeida Silva Teixeira
Protective mechanical ventilation in suspected influenza infection
Revista da Sociedade Brasileira de Medicina Tropical
Acute respiratory distress syndrome
Influenza virus
Mechanical ventilation
title Protective mechanical ventilation in suspected influenza infection
title_full Protective mechanical ventilation in suspected influenza infection
title_fullStr Protective mechanical ventilation in suspected influenza infection
title_full_unstemmed Protective mechanical ventilation in suspected influenza infection
title_short Protective mechanical ventilation in suspected influenza infection
title_sort protective mechanical ventilation in suspected influenza infection
topic Acute respiratory distress syndrome
Influenza virus
Mechanical ventilation
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100662&tlng=en
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AT marciasouzavolpe protectivemechanicalventilationinsuspectedinfluenzainfection
AT marcelobrittopassosamato protectivemechanicalventilationinsuspectedinfluenzainfection
AT adilhamissonruamicheletti protectivemechanicalventilationinsuspectedinfluenzainfection
AT lucianadealmeidasilvateixeira protectivemechanicalventilationinsuspectedinfluenzainfection