A distributable LC-MS/MS method for the measurement of serum thyroglobulin

A distributable LC-MS/MS method for the measurement of serum thyroglobulin

Background: Despite its clear advantages over immunoassay-based testing, the measurement of serum thyroglobulin by mass spectrometry remains limited to a handful of institutions. Slow adoption by clinical laboratories could reflect limited accessibility to existing methods that have sensitivity comp...

Full description

Bibliographic Details
Main Authors:	Junyan Shi, William S. Phipps, Benjamin Y. Owusu, Clark M. Henderson, Thomas J. Laha, Jessica O. Becker, Morteza Razavi, Michelle A. Emrick, Andrew N. Hoofnagle
Format:	Article
Language:	English
Published:	Elsevier 2022-11-01
Series:	Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:	Thyroglobulin Differentiated thyroid cancer Autoantibody Mass spectrometry
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667145X22000396

Similar Items

Clinical laboratory verification of thyroglobulin concentrations in the presence of autoantibodies to thyroglobulin: comparison of EIA, radioimmunoassay and LC MS/MS measurements in an Urban Hospital
by: Sarah E. Wheeler, et al.
Published: (2017-12-01)

Reactivity of anti-thyroid antibodies to thyroglobulin tryptic fragments: comparison of autoimmune and non-autoimmune thyroid diseases
by: L.H.B. Boechat, et al.
Published: (1999-04-01)

Modulation of Serum Anti-thyroglobulin and Anti-thyroid Microsomal Autoantibody Levels by Levamisole in Patients With Oral Lichen Planus
by: Hung-Pin Lin, et al.
Published: (2011-03-01)

Measuring thyroglobulin concentrations in patients with differentiated thyroid carcinoma
by: Savin Svetlana, et al.
Published: (2010-01-01)

Efficacy Analysis of 131I Therapy in Serum Thyroglobulin Antibody Positive Differentiated Thyroid Carcinoma with Distant Metastasis
by: BAI Xin, WU Xinyu, ZHAO Zun, LIU Shuxin, LIU Simiao, XUE Yuhang, XU Junling, GAO Yongju
Published: (2024-05-01)

Prognostic Value of Serum Thyroglobulin and Anti-Thyroglobulin Antibody in Thyroid Carcinoma Patients following Thyroidectomy
by: Hashem O. Zahra, et al.
Published: (2021-11-01)

Serum thyroglobulin evaluation on LC-MS/MS and immunoassay in TgAb-positive patients with papillary thyroid carcinoma
by: Eijun Nishihara, et al.
Published: (2023-01-01)

Clinical and Laboratory Aspects of Thyroglobulin and Thyroglobulin Antibody in Differentiated Thyroid Carcinoma
by: Hani Ajrina Zulkeflee, et al.
Published: (2022-07-01)

ANTI-THYROGLOBULIN ANTIBODIES IN PATIENTS WITH AUTOIMMUNE THYROIDITIS DURING L-THYROXINE TREATMENT
by: O. A. Shashkova, et al.
Published: (2014-07-01)

ANTI-THYROGLOBULIN ANTIBODIES IN PATIENTS WITH AUTOIMMUNE THYROIDITIS DURING L-THYROXINE TREATMENT
by: O. A. Shashkova, et al.
Published: (2014-07-01)

Does autoimmunity against thyroglobulin play a role in the pathogenesis of Graves’ ophthalmopathy: a review
by: Shanmuganathan T, et al.
Published: (2015-12-01)

Significance of Thyroglobulin in Thyroid Diseases Detected by the Immunoperoxidase Method
by: Paisal Parichatikanond, et al.
Published: (2020-08-01)

Application of thyroglobulin and anti-thyroglobulin antibody combined with emission computed tomography in the adjuvant diagnosis of differentiated thyroid carcinoma
by: Nan Jiang, et al.
Published: (2023-12-01)

Clinical irrelevance of lower titer thyroglobulin autoantibodies in patients with differentiated thyroid carcinoma
by: Bernadette L Dekker, et al.
Published: (2023-01-01)

Thyroglobulin/thyrotropin ratio for predicting long-term response in differentiated thyroid carcinoma: a retrospective study
by: Adriano Francisco De Marchi Junior, et al.
Published: (2021-07-01)

Prevalence of thyroid autoantibody positivity in women with infertility: a systematic review and meta-analysis
by: Yingqin Huang, et al.
Published: (2024-11-01)

Elevated thyroglobulin level is associated with dysfunction of regulatory T cells in patients with thyroid nodules
by: Yun Hu, et al.
Published: (2019-03-01)

Pre-Ablation Thyroglobulin Levels and Persistence / Recurrence Associated to Early Differentiated Thyroid Cancer
by: Arturo Mejía López, et al.
Published: (2014-01-01)

Predictive value of highly sensitive basal versus stimulated thyroglobulin measurement in long-term follow-up of thyroid cancer
by: Kim Magaly Pabst, et al.
Published: (2023-01-01)

Struma ovarii associated with increased serum thyroglobulin
by: Na Su, et al.
Published: (2023-12-01)

Clinical analysis of thyroglobulin antibody and thyroid peroxidase antibody and their association with vitiligo
by: Yifen Yang, et al.
Published: (2014-01-01)

Cervical lymphatic malformation demonstrating thyroglobulin on fine needle aspirate washout
by: Ashwin Agnihotri, et al.
Published: (2020-12-01)

Development and validation of a novel LC-MS/MS assay for C-peptide in human serum
by: Benjamin Y. Owusu, et al.
Published: (2021-01-01)

Clinical significance of thyroglobulin autoantibodies enhancement in patients with differentiated thyroid cancer after thyroidectomy and radioiodine therapy
Published: (2013-09-01)

Comparison of Thyroglobulin Measurements Using Three Different Immunoassay Kits: A BRAMHS Tg-Plus RIA Kit, a BRAMHS hTg Sensitive Kryptor Kit, and a Beckman Coulter ACCESS Immunoassay Kit
by: Mijin Kim, et al.
Published: (2016-09-01)

Rapid One-Step Modified Technique in the Evaluation of Thyroglobulin by the Immunoradiometric Assay (IRMA) for Monitoring Differentiated Thyroid Carcinoma Patients
by: Sirinya Worrasir, et al.
Published: (2020-07-01)

The role of anti-TPO as an additional analytical marker in thyroid disease patients in Erbil City
by: Ronia Shawkat Kawther ,, et al.
Published: (2022-12-01)

Comparing the efficacy of thyroglobulin and thyroglobulin/ thyroid-stimulating hormone ratio models in predicting a successful response to radioactive iodine therapy
by: Yanli Ju, et al.
Published: (2023-01-01)

Predictors of recurrence after total thyroidectomy in 1,611 patients with papillary thyroid carcinoma: postoperative stimulated serum thyroglobulin and ATA initial and dynamic risk assessment
by: Andre Ywata de Carvalho, et al.
Published: (2024-06-01)

Preablative Stimulated Thyroglobulin and Thyroglobulin Reduction Index as Decision-Making Markers for Second Radioactive Iodine Therapy in Patients with Structural Incomplete Response
by: Wang L, et al.
Published: (2021-07-01)

The role of thyroglobulin doubling time in differentiated thyroid cancer: a meta-analysis
by: Luca Giovanella, et al.
Published: (2022-04-01)

Breast Cancer and Autoimmune Thyroid Disease Relationship: Can Hormonal Factors or Thyroglobulin Gene Polymorphism Be the Common Factor?
by: Tolga Özmen, et al.
Published: (2014-01-01)

The Role of Intraoperative Thyroglobuline Level of Lymph Node in the Management of Papillary Thyroid Cancer (Determination of a Cutoff Point)
by: Mohsen Kolahdouzan, et al.
Published: (2017-01-01)

Effect of therapeutic radioiodine activity on ablation response in differentiated thyroid cancer patients with cut-off serum thyroglobulin levels after 2 weeks of thyroid hormone withdrawal: a retrospective study
by: Ji Young Lee, et al.
Published: (2022-12-01)

Thyroglobulin measurement in the needle washout for diagnosis of lymph node metastases of differentiated thyroid cancer
by: N. V. Severskaya, et al.
Published: (2023-06-01)

Multiplexed quantification of insulin and C-peptide by LC-MS/MS without the use of antibodies
by: North Foulon, et al.
Published: (2022-08-01)

Diagnosis of thyroid disease: Principles and problems
by: Žarković Miloš
Published: (2010-01-01)

Impact of 18F-FDG PET/CT on treatment of patients with differentiated thyroid carcinoma, negative 131I whole body scan and elevated serum thyroglobulin
by: Raef Boktor, et al.
Published: (2022-01-01)

Clinical and molecular study of patients with thyroid dyshormogenesis and variants in the thyroglobulin gene
by: Mónica Fernández-Cancio, et al.
Published: (2024-07-01)

The effect of positive thyroglobulin antibodies on the prognosis and treatment response in patients with papillary thyroid carcinoma
by: Mojgan Sanjari, et al.
Published: (2024-02-01)