Eurycomanone and Eurycomanol from Eurycoma longifolia Jack as Regulators of Signaling Pathways Involved in Proliferation, Cell Death and Inflammation

Eurycomanone and Eurycomanol from Eurycoma longifolia Jack as Regulators of Signaling Pathways Involved in Proliferation, Cell Death and Inflammation

Eurycomanone and eurycomanol are two quassinoids from the roots of Eurycoma longifolia Jack. The aim of this study was to assess the bioactivity of these compounds in Jurkat and K562 human leukemia cell models compared to peripheral blood mononuclear cells from healthy donors. Both eurycomanone and...

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Bibliographic Details
Main Authors: Shéhérazade Hajjouli, Sébastien Chateauvieux, Marie-Hélène Teiten, Barbora Orlikova, Marc Schumacher, Mario Dicato, Chee-Yan Choo, Marc Diederich
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
eurycomanone
eurycomanol
Eurycoma longifolia Jack
NF-κB
proliferation
cell death
Online Access:http://www.mdpi.com/1420-3049/19/9/14649

Internet

http://www.mdpi.com/1420-3049/19/9/14649

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