Topical antibiotics in the management of corneal ulcer
A total of 82 patients suffering from corneal ulcer were treated with framycetin 0.5%, gentamicin 3 mg./ml, chloramphenicol 0.4% and a neomycin combination containing Polymixin B sulphate 5000 u, neomycin sulphate 1700 u and gramicidin 0.025 mg/mL in a Randomised comparative st...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
1988-01-01
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| Series: | Indian Journal of Ophthalmology |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=1988;volume=36;issue=2;spage=95;epage=97;aulast=Reddy |
| _version_ | 1811253655077126144 |
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| author | Reddy P |
| author_facet | Reddy P |
| author_sort | Reddy P |
| collection | DOAJ |
| description | A total of 82 patients suffering from corneal ulcer were treated with framycetin 0.5%, gentamicin 3 mg./ml, chloramphenicol 0.4% and a neomycin combination containing Polymixin B sulphate 5000 u, neomycin sulphate 1700 u and gramicidin 0.025 mg/mL in a Randomised comparative study. The commonest organism isolated was Staphylococcus followed by Pneumococcus, Streptococcus and Pseudomonas. The in vitro sensitivity of these isolates to framycetin was higher than that to others Framycetin produced both earlier and a greater degree of improvement in mean score of signs and symptoms than the other antibiotics. It can thus be concluded that framycetin has a better profile of antibacterial activity and clinical efficacy than some other commonly used topical antibiotics in the treatment of corneal ulcer. |
| first_indexed | 2024-04-12T16:54:18Z |
| format | Article |
| id | doaj.art-07918ed9c15547fd87de492c10798164 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 |
| language | English |
| last_indexed | 2024-04-12T16:54:18Z |
| publishDate | 1988-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-07918ed9c15547fd87de492c107981642022-12-22T03:24:17ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381988-01-013629597Topical antibiotics in the management of corneal ulcerReddy PA total of 82 patients suffering from corneal ulcer were treated with framycetin 0.5%, gentamicin 3 mg./ml, chloramphenicol 0.4% and a neomycin combination containing Polymixin B sulphate 5000 u, neomycin sulphate 1700 u and gramicidin 0.025 mg/mL in a Randomised comparative study. The commonest organism isolated was Staphylococcus followed by Pneumococcus, Streptococcus and Pseudomonas. The in vitro sensitivity of these isolates to framycetin was higher than that to others Framycetin produced both earlier and a greater degree of improvement in mean score of signs and symptoms than the other antibiotics. It can thus be concluded that framycetin has a better profile of antibacterial activity and clinical efficacy than some other commonly used topical antibiotics in the treatment of corneal ulcer.http://www.ijo.in/article.asp?issn=0301-4738;year=1988;volume=36;issue=2;spage=95;epage=97;aulast=Reddy |
| spellingShingle | Reddy P Topical antibiotics in the management of corneal ulcer Indian Journal of Ophthalmology |
| title | Topical antibiotics in the management of corneal ulcer |
| title_full | Topical antibiotics in the management of corneal ulcer |
| title_fullStr | Topical antibiotics in the management of corneal ulcer |
| title_full_unstemmed | Topical antibiotics in the management of corneal ulcer |
| title_short | Topical antibiotics in the management of corneal ulcer |
| title_sort | topical antibiotics in the management of corneal ulcer |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=1988;volume=36;issue=2;spage=95;epage=97;aulast=Reddy |
| work_keys_str_mv | AT reddyp topicalantibioticsinthemanagementofcornealulcer |