The Role of Co-chaperones in Synaptic Proteostasis and Neurodegenerative Disease
Synapses must be preserved throughout an organism's lifespan to allow for normal brain function and behavior. Synapse maintenance is challenging given the long distances between the termini and the cell body, reliance on axonal transport for delivery of newly synthesized presynaptic proteins, a...
Main Authors: | Erica L. Gorenberg, Sreeganga S. Chandra |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-05-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fnins.2017.00248/full |
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