Expression levels of circulating miRNAs as biomarkers during multimodal treatment of rectal cancer - TiMiSNAR-mirna: a substudy of the TiMiSNAR Trial (NCT03962088)

Expression levels of circulating miRNAs as biomarkers during multimodal treatment of rectal cancer - TiMiSNAR-mirna: a substudy of the TiMiSNAR Trial (NCT03962088)

Abstract Background Neoadjuvant chemoradiotherapy followed by surgery is the mainstay treatment for locally advanced rectal cancer, leading to significant decrease in tumor size (downsizing) and a shift towards earlier disease stage (downstaging). Extensive histopathological work-up of the tumor spe...

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Bibliographic Details
Main Authors: Igor Monsellato, Elisabetta Garibaldi, Elisa Cassinotti, Ludovica Baldari, Luigi Boni, Ugo Elmore, Roberto Delpini, Riccardo Rosati, Roberto Perinotti, Filippo Alongi, Elisa Bertocchi, Stefania Gori, Giacomo Ruffo, Graziano Pernazza, Fabio Pulighe, Carlo De Nisco, Emilio Morpurgo, Tania Contardo, Enzo Mammano, Federico Perna, Benedetta Menegatti, Andrea Coratti, Piero Buccianti, Riccardo Balestri, Cristina Ceccarelli, Davide Cavaliere, Leonardo Solaini, Giorgio Ercolani, Elena Traverso, Vittorio Fusco, Valter Torri, Sara Orecchia
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Trials
Subjects:
Colorectal cancer
miRNA
Neoadjuvant treatment
Biomarkers
Translational research
Online Access:http://link.springer.com/article/10.1186/s13063-020-04568-9

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