Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort

Background: The maternal cardiovascular system undergoes progressive adaptations throughout pregnancy, causing blood pressure fluctuations. However, no consensus has been established on its normal variation in uncomplicated pregnancies. Objective: To describe the variation in systolic blood pressure...

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Main Authors: Fernanda Rebelo, Dayana Rodrigues Farias, Roberta Hack Mendes, Michael Maia Schlüssel, Gilberto Kac
Format: Article
Language:English
Published: Sociedade Brasileira de Cardiologia (SBC) 2015-04-01
Series:Arquivos Brasileiros de Cardiologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015000400004&lng=en&tlng=en
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author Fernanda Rebelo
Dayana Rodrigues Farias
Roberta Hack Mendes
Michael Maia Schlüssel
Gilberto Kac
author_facet Fernanda Rebelo
Dayana Rodrigues Farias
Roberta Hack Mendes
Michael Maia Schlüssel
Gilberto Kac
author_sort Fernanda Rebelo
collection DOAJ
description Background: The maternal cardiovascular system undergoes progressive adaptations throughout pregnancy, causing blood pressure fluctuations. However, no consensus has been established on its normal variation in uncomplicated pregnancies. Objective: To describe the variation in systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels during pregnancy according to early pregnancy body mass index (BMI). Methods: SBP and DBP were measured during the first, second and third trimesters and at 30-45 days postpartum in a prospective cohort of 189 women aged 20-40 years. BMI (kg/m2) was measured up to the 13th gestational week and classified as normal-weight (<25.0) or excessive weight (≥25.0). Longitudinal linear mixed-effects models were used for statistical analysis. Results: A decrease in SBP and DBP was observed from the first to the second trimester (βSBP=-0.394; 95%CI: -0.600- -0.188 and βDBP=-0.617; 95%CI: -0.780- -0.454), as was an increase in SBP and DBP up to 30-45 postpartum days (βSBP=0.010; 95%CI: 0.006-0.014 and βDBP=0.015; 95%CI: 0.012-0.018). Women with excessive weight at early pregnancy showed higher mean SBP in all gestational trimesters, and higher mean DBP in the first and third trimesters. Excessive early pregnancy BMI was positively associated with prospective changes in SBP (βSBP=7.055; 95%CI: 4.499-9.610) and in DBP (βDBP=3.201; 95%CI: 1.136-5.266). Conclusion: SBP and DBP decreased from the first to the second trimester and then increased up to the postpartum period. Women with excessive early pregnancy BMI had higher SBP and DBP than their normal-weight counterparts throughout pregnancy, but not in the postpartum period.
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spelling doaj.art-07994367a43e437ab7512bda80ffc1ea2022-12-22T00:32:49ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia1678-41702015-04-01104428429110.5935/abc.20150007S0066-782X2015000400004Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian CohortFernanda RebeloDayana Rodrigues FariasRoberta Hack MendesMichael Maia SchlüsselGilberto KacBackground: The maternal cardiovascular system undergoes progressive adaptations throughout pregnancy, causing blood pressure fluctuations. However, no consensus has been established on its normal variation in uncomplicated pregnancies. Objective: To describe the variation in systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels during pregnancy according to early pregnancy body mass index (BMI). Methods: SBP and DBP were measured during the first, second and third trimesters and at 30-45 days postpartum in a prospective cohort of 189 women aged 20-40 years. BMI (kg/m2) was measured up to the 13th gestational week and classified as normal-weight (<25.0) or excessive weight (≥25.0). Longitudinal linear mixed-effects models were used for statistical analysis. Results: A decrease in SBP and DBP was observed from the first to the second trimester (βSBP=-0.394; 95%CI: -0.600- -0.188 and βDBP=-0.617; 95%CI: -0.780- -0.454), as was an increase in SBP and DBP up to 30-45 postpartum days (βSBP=0.010; 95%CI: 0.006-0.014 and βDBP=0.015; 95%CI: 0.012-0.018). Women with excessive weight at early pregnancy showed higher mean SBP in all gestational trimesters, and higher mean DBP in the first and third trimesters. Excessive early pregnancy BMI was positively associated with prospective changes in SBP (βSBP=7.055; 95%CI: 4.499-9.610) and in DBP (βDBP=3.201; 95%CI: 1.136-5.266). Conclusion: SBP and DBP decreased from the first to the second trimester and then increased up to the postpartum period. Women with excessive early pregnancy BMI had higher SBP and DBP than their normal-weight counterparts throughout pregnancy, but not in the postpartum period.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015000400004&lng=en&tlng=enPressão ArterialGestantesGravidezÍndice de Massa CorporalEstudos de Coortes
spellingShingle Fernanda Rebelo
Dayana Rodrigues Farias
Roberta Hack Mendes
Michael Maia Schlüssel
Gilberto Kac
Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort
Arquivos Brasileiros de Cardiologia
Pressão Arterial
Gestantes
Gravidez
Índice de Massa Corporal
Estudos de Coortes
title Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort
title_full Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort
title_fullStr Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort
title_full_unstemmed Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort
title_short Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort
title_sort blood pressure variation throughout pregnancy according to early gestational bmi a brazilian cohort
topic Pressão Arterial
Gestantes
Gravidez
Índice de Massa Corporal
Estudos de Coortes
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2015000400004&lng=en&tlng=en
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