Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatricians
Cytomegalovirus (CMV) pneumonitis infections might present mild or severe illnesses and need sophisticated diagnostic tools, so it remains a diagnostic challenge. We reported five infants diagnosed with CMV pneumonitis who were initially and undiagnosed by the pediatrician in secondary private or pu...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | IDCases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250923000483 |
| _version_ | 1797809822350966784 |
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| author | Djatnika Setiabudi Ria Resti Sukur Harry Galuh Nugraha Heda Melinda Nataprawira |
| author_facet | Djatnika Setiabudi Ria Resti Sukur Harry Galuh Nugraha Heda Melinda Nataprawira |
| author_sort | Djatnika Setiabudi |
| collection | DOAJ |
| description | Cytomegalovirus (CMV) pneumonitis infections might present mild or severe illnesses and need sophisticated diagnostic tools, so it remains a diagnostic challenge. We reported five infants diagnosed with CMV pneumonitis who were initially and undiagnosed by the pediatrician in secondary private or public health hospitals with no improvement with standard and escalation of antibiotics treatment for bronchopneumonia as the initial diagnoses. As all cases occurred during the COVID-19 pandemic, they proved negative COVID-19 identified by polymerase chain reaction (PCR) SARS-CoV-2. We diagnosed acquired perinatal pneumonitis CMV in all claims based on clinical criteria, imaging studies, CMV serology, and PCR-CMV urinary tests as diagnostic tools. They showed clinical improvement after two weeks of valganciclovir therapy. Other organs’ involvement was considered to be evaluated, including brain-evoked response audiometry (BERA) and eye examination. The physician should consider the possibility of CMV pneumonitis, who did not respond to standard and escalation of antibiotics treatment after initial diagnoses of bronchopneumonia. |
| first_indexed | 2024-03-13T06:58:35Z |
| format | Article |
| id | doaj.art-079ed0b847124b20a7f175531c1b00ec |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-03-13T06:58:35Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-079ed0b847124b20a7f175531c1b00ec2023-06-07T04:48:05ZengElsevierIDCases2214-25092023-01-0132e01724Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatriciansDjatnika Setiabudi0Ria Resti Sukur1Harry Galuh Nugraha2Heda Melinda Nataprawira3Department of Child Health, Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung, IndonesiaDepartment of Child Health, Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung, IndonesiaDepartment of Radiology, Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung, IndonesiaĪDepartment of Child Health, Hasan Sadikin General Hospital/Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Correspondence to: Division-Department of Child Health, Universitas Padjadjaran, Hasan Sadikin General Hospital, Jalan Pasteur no 38, Postcode 40161, Bandung, Indonesia.Cytomegalovirus (CMV) pneumonitis infections might present mild or severe illnesses and need sophisticated diagnostic tools, so it remains a diagnostic challenge. We reported five infants diagnosed with CMV pneumonitis who were initially and undiagnosed by the pediatrician in secondary private or public health hospitals with no improvement with standard and escalation of antibiotics treatment for bronchopneumonia as the initial diagnoses. As all cases occurred during the COVID-19 pandemic, they proved negative COVID-19 identified by polymerase chain reaction (PCR) SARS-CoV-2. We diagnosed acquired perinatal pneumonitis CMV in all claims based on clinical criteria, imaging studies, CMV serology, and PCR-CMV urinary tests as diagnostic tools. They showed clinical improvement after two weeks of valganciclovir therapy. Other organs’ involvement was considered to be evaluated, including brain-evoked response audiometry (BERA) and eye examination. The physician should consider the possibility of CMV pneumonitis, who did not respond to standard and escalation of antibiotics treatment after initial diagnoses of bronchopneumonia.http://www.sciencedirect.com/science/article/pii/S2214250923000483CMV pneumonitisPCR-CMV urinaryRespiratory infectionCase report |
| spellingShingle | Djatnika Setiabudi Ria Resti Sukur Harry Galuh Nugraha Heda Melinda Nataprawira Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatricians IDCases CMV pneumonitis PCR-CMV urinary Respiratory infection Case report |
| title | Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatricians |
| title_full | Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatricians |
| title_fullStr | Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatricians |
| title_full_unstemmed | Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatricians |
| title_short | Cytomegalovirus pneumonitis in infants: The challenge in diagnosis among pediatricians |
| title_sort | cytomegalovirus pneumonitis in infants the challenge in diagnosis among pediatricians |
| topic | CMV pneumonitis PCR-CMV urinary Respiratory infection Case report |
| url | http://www.sciencedirect.com/science/article/pii/S2214250923000483 |
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