Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana

Abstract Background Diabetes and depression are both chronic debilitating conditions, and their coexistence has been associated with adverse outcomes. In this study, we investigated the association between glycaemic control and depression in type 2 diabetes (T2DM) patients attending a tertiary healt...

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Main Authors: Josephine Akpalu, Ernest Yorke, Joana Ainuson-Quampah, Williams Balogun, Kwame Yeboah
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Psychiatry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12888-018-1933-2
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author Josephine Akpalu
Ernest Yorke
Joana Ainuson-Quampah
Williams Balogun
Kwame Yeboah
author_facet Josephine Akpalu
Ernest Yorke
Joana Ainuson-Quampah
Williams Balogun
Kwame Yeboah
author_sort Josephine Akpalu
collection DOAJ
description Abstract Background Diabetes and depression are both chronic debilitating conditions, and their coexistence has been associated with adverse outcomes. In this study, we investigated the association between glycaemic control and depression in type 2 diabetes (T2DM) patients attending a tertiary healthcare facility in Ghana. Methodology In a cross-sectional study design, Patient Health Questionnare-9 (PHQ-9) was used to assess depression in 400 T2DM, aged 30–65 years. Anthropometric characteristics and blood pressure were measured. Venous blood was collected to measure the levels of glycated haemoglobin (HbA1c). Results The prevalence of depression was 31.3% among T2DM patients. Female gender, being unmarried, frequent intake of alcohol, previous smoking status and insulin use were associated with increased odds of depression, whereas being educated above basic school level was associated with a decreased odds of depression. In a multivariable logistic regression model, being unmarried and poor glycaemic control were associated with an increase in odds of depression after adjusting for age, gender, and social factors. The association between depression and glycaemic control was attenuated when clinical factors were introduced into the model. Conclusion In our study population, we found that depression is common among Ghanaians with T2DM, and not associated with poor glycaemic control in a fully multivariable-adjusted model.
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spelling doaj.art-07a39de50f3f46dbb01d123661cc4a212022-12-21T23:59:44ZengBMCBMC Psychiatry1471-244X2018-11-011811710.1186/s12888-018-1933-2Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in GhanaJosephine Akpalu0Ernest Yorke1Joana Ainuson-Quampah2Williams Balogun3Kwame Yeboah4Department of Medicine & Therapeutics, School of Medicine & Dentistry, University of GhanaDepartment of Medicine & Therapeutics, School of Medicine & Dentistry, University of GhanaDepartment of Dietetics, School of Biomedical and Allied Health Sciences, University of GhanaCollege of Medicine, University of IbadanDepartment of Physiology, School of Biomedical and Allied Health Sciences, University of GhanaAbstract Background Diabetes and depression are both chronic debilitating conditions, and their coexistence has been associated with adverse outcomes. In this study, we investigated the association between glycaemic control and depression in type 2 diabetes (T2DM) patients attending a tertiary healthcare facility in Ghana. Methodology In a cross-sectional study design, Patient Health Questionnare-9 (PHQ-9) was used to assess depression in 400 T2DM, aged 30–65 years. Anthropometric characteristics and blood pressure were measured. Venous blood was collected to measure the levels of glycated haemoglobin (HbA1c). Results The prevalence of depression was 31.3% among T2DM patients. Female gender, being unmarried, frequent intake of alcohol, previous smoking status and insulin use were associated with increased odds of depression, whereas being educated above basic school level was associated with a decreased odds of depression. In a multivariable logistic regression model, being unmarried and poor glycaemic control were associated with an increase in odds of depression after adjusting for age, gender, and social factors. The association between depression and glycaemic control was attenuated when clinical factors were introduced into the model. Conclusion In our study population, we found that depression is common among Ghanaians with T2DM, and not associated with poor glycaemic control in a fully multivariable-adjusted model.http://link.springer.com/article/10.1186/s12888-018-1933-2DepressionType 2 diabetes mellitusGlycaemic controlGhana
spellingShingle Josephine Akpalu
Ernest Yorke
Joana Ainuson-Quampah
Williams Balogun
Kwame Yeboah
Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana
BMC Psychiatry
Depression
Type 2 diabetes mellitus
Glycaemic control
Ghana
title Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana
title_full Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana
title_fullStr Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana
title_full_unstemmed Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana
title_short Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana
title_sort depression and glycaemic control among type 2 diabetes patients a cross sectional study in a tertiary healthcare facility in ghana
topic Depression
Type 2 diabetes mellitus
Glycaemic control
Ghana
url http://link.springer.com/article/10.1186/s12888-018-1933-2
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