Diagnostic accuracy of magnetic resonance, computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases.
<h4>Purpose</h4>We compared diagnostic performance of Magnetic Resonance (MR), Computed Tomography (CT) and Ultrasound (US) with (CEUS) and without contrast medium to identify peribiliary metastasis.<h4>Methods</h4>We identified 35 subjects with histological proven peribiliar...
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179951&type=printable |
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| author | Vincenza Granata Roberta Fusco Orlando Catalano Antonio Avallone Raffaele Palaia Gerardo Botti Fabiana Tatangelo Francesco Granata Marco Cascella Francesco Izzo Antonella Petrillo |
| author_facet | Vincenza Granata Roberta Fusco Orlando Catalano Antonio Avallone Raffaele Palaia Gerardo Botti Fabiana Tatangelo Francesco Granata Marco Cascella Francesco Izzo Antonella Petrillo |
| author_sort | Vincenza Granata |
| collection | DOAJ |
| description | <h4>Purpose</h4>We compared diagnostic performance of Magnetic Resonance (MR), Computed Tomography (CT) and Ultrasound (US) with (CEUS) and without contrast medium to identify peribiliary metastasis.<h4>Methods</h4>We identified 35 subjects with histological proven peribiliary metastases who underwent CEUS, CT and MR study. Four radiologists evaluated the presence of peribiliary lesions, using a 4-point confidence scale. Echogenicity, density and T1-Weigthed (T1-W), T2-W and Diffusion Weighted Imaging (DWI) signal intensity as well as the enhancement pattern during contrast studies on CEUS, CT and MR so as hepatobiliary-phase on MRI was assessed.<h4>Results</h4>All lesions were detected by MR. CT detected 8 lesions, while US/CEUS detected one lesion. According to the site of the lesion, respect to the bile duct and hepatic parenchyma: 19 (54.3%) were periductal, 15 (42.8%) were intra-periductal and 1 (2.8%) was periductal-intrahepatic. According to the confidence scale MRI had the best diagnostic performance to assess the lesion. CT obtained lower diagnostic performance. There was no significant difference in MR signal intensity and contrast enhancement among all metastases (p>0.05). There was no significant difference in CT density and contrast enhancement among all metastases (p>0.05).<h4>Conclusions</h4>MRI is the method of choice for biliary tract tumors but it does not allow a correct differential diagnosis among different histological types of metastasis. The presence of biliary tree dilatation without hepatic lesions on CT and US/CEUS study may be an indirect sign of peribiliary metastases and for this reason the patient should be evaluated by MRI. |
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| id | doaj.art-07aa4428e48a4c05a558939a4ae70a71 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2025-03-14T14:07:06Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-07aa4428e48a4c05a558939a4ae70a712025-02-27T05:38:35ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01126e017995110.1371/journal.pone.0179951Diagnostic accuracy of magnetic resonance, computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases.Vincenza GranataRoberta FuscoOrlando CatalanoAntonio AvalloneRaffaele PalaiaGerardo BottiFabiana TatangeloFrancesco GranataMarco CascellaFrancesco IzzoAntonella Petrillo<h4>Purpose</h4>We compared diagnostic performance of Magnetic Resonance (MR), Computed Tomography (CT) and Ultrasound (US) with (CEUS) and without contrast medium to identify peribiliary metastasis.<h4>Methods</h4>We identified 35 subjects with histological proven peribiliary metastases who underwent CEUS, CT and MR study. Four radiologists evaluated the presence of peribiliary lesions, using a 4-point confidence scale. Echogenicity, density and T1-Weigthed (T1-W), T2-W and Diffusion Weighted Imaging (DWI) signal intensity as well as the enhancement pattern during contrast studies on CEUS, CT and MR so as hepatobiliary-phase on MRI was assessed.<h4>Results</h4>All lesions were detected by MR. CT detected 8 lesions, while US/CEUS detected one lesion. According to the site of the lesion, respect to the bile duct and hepatic parenchyma: 19 (54.3%) were periductal, 15 (42.8%) were intra-periductal and 1 (2.8%) was periductal-intrahepatic. According to the confidence scale MRI had the best diagnostic performance to assess the lesion. CT obtained lower diagnostic performance. There was no significant difference in MR signal intensity and contrast enhancement among all metastases (p>0.05). There was no significant difference in CT density and contrast enhancement among all metastases (p>0.05).<h4>Conclusions</h4>MRI is the method of choice for biliary tract tumors but it does not allow a correct differential diagnosis among different histological types of metastasis. The presence of biliary tree dilatation without hepatic lesions on CT and US/CEUS study may be an indirect sign of peribiliary metastases and for this reason the patient should be evaluated by MRI.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179951&type=printable |
| spellingShingle | Vincenza Granata Roberta Fusco Orlando Catalano Antonio Avallone Raffaele Palaia Gerardo Botti Fabiana Tatangelo Francesco Granata Marco Cascella Francesco Izzo Antonella Petrillo Diagnostic accuracy of magnetic resonance, computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases. PLoS ONE |
| title | Diagnostic accuracy of magnetic resonance, computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases. |
| title_full | Diagnostic accuracy of magnetic resonance, computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases. |
| title_fullStr | Diagnostic accuracy of magnetic resonance, computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases. |
| title_full_unstemmed | Diagnostic accuracy of magnetic resonance, computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases. |
| title_short | Diagnostic accuracy of magnetic resonance, computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases. |
| title_sort | diagnostic accuracy of magnetic resonance computed tomography and contrast enhanced ultrasound in radiological multimodality assessment of peribiliary liver metastases |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179951&type=printable |
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