Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma

Glioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy, and radiotherapy are the main treatment meth...

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Main Authors: Yandong Xie, Yuhan Han, Xuefeng Zhang, Hongwei Ma, Linfeng Li, Rutong Yu, Hongmei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.633827/full
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author Yandong Xie
Yandong Xie
Yandong Xie
Yuhan Han
Yuhan Han
Yuhan Han
Xuefeng Zhang
Hongwei Ma
Linfeng Li
Rutong Yu
Rutong Yu
Hongmei Liu
Hongmei Liu
author_facet Yandong Xie
Yandong Xie
Yandong Xie
Yuhan Han
Yuhan Han
Yuhan Han
Xuefeng Zhang
Hongwei Ma
Linfeng Li
Rutong Yu
Rutong Yu
Hongmei Liu
Hongmei Liu
author_sort Yandong Xie
collection DOAJ
description Glioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy, and radiotherapy are the main treatment methods for glioma. With the development of clinical trials and traditional treatment techniques, radiotherapy for glioma has increasingly exposed defects in the treatment effect. In order to improve the bottleneck of radiotherapy for glioma, people have done a lot of work; among this, nano-radiosensitizers have offered a novel and potential treatment method. Compared with conventional radiotherapy, nanotechnology can overcome the blood–brain barrier and improve the sensitivity of glioma to radiotherapy. This paper focuses on the research progress of nano-radiosensitizers in radiotherapy for glioma.
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publisher Frontiers Media S.A.
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spelling doaj.art-07ac78f9297d4529baa3bab28836bfec2022-12-21T20:26:12ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2021-03-011110.3389/fonc.2021.633827633827Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of GliomaYandong Xie0Yandong Xie1Yandong Xie2Yuhan Han3Yuhan Han4Yuhan Han5Xuefeng Zhang6Hongwei Ma7Linfeng Li8Rutong Yu9Rutong Yu10Hongmei Liu11Hongmei Liu12Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, ChinaDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, ChinaDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, ChinaInstitute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, ChinaDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, ChinaDepartment of Neurosurgery, Suqian First People’s Hospital, Suqian, ChinaInstitute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, ChinaInstitute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, ChinaInstitute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, ChinaInstitute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, ChinaDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, ChinaInstitute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, ChinaDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, ChinaGlioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy, and radiotherapy are the main treatment methods for glioma. With the development of clinical trials and traditional treatment techniques, radiotherapy for glioma has increasingly exposed defects in the treatment effect. In order to improve the bottleneck of radiotherapy for glioma, people have done a lot of work; among this, nano-radiosensitizers have offered a novel and potential treatment method. Compared with conventional radiotherapy, nanotechnology can overcome the blood–brain barrier and improve the sensitivity of glioma to radiotherapy. This paper focuses on the research progress of nano-radiosensitizers in radiotherapy for glioma.https://www.frontiersin.org/articles/10.3389/fonc.2021.633827/fullnano-radiosensitizerradiotherapyradiation sensitizationnanoparticlesglioma
spellingShingle Yandong Xie
Yandong Xie
Yandong Xie
Yuhan Han
Yuhan Han
Yuhan Han
Xuefeng Zhang
Hongwei Ma
Linfeng Li
Rutong Yu
Rutong Yu
Hongmei Liu
Hongmei Liu
Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
Frontiers in Oncology
nano-radiosensitizer
radiotherapy
radiation sensitization
nanoparticles
glioma
title Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_full Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_fullStr Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_full_unstemmed Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_short Application of New Radiosensitizer Based on Nano-Biotechnology in the Treatment of Glioma
title_sort application of new radiosensitizer based on nano biotechnology in the treatment of glioma
topic nano-radiosensitizer
radiotherapy
radiation sensitization
nanoparticles
glioma
url https://www.frontiersin.org/articles/10.3389/fonc.2021.633827/full
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