Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells
Abstract Background Rodent and human β-cells are differentially susceptible to the “lipotoxic” effects of long-chain saturated fatty acids (LC-SFA) but the factors accounting for this are unclear. Here, we have studied the intracellular disposition of the LC-SFA palmitate in human vs rodent β–cells...
| Главные авторы: | , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Nature Publishing Group
2022-04-01
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| Серии: | Nutrition & Diabetes |
| Online-ссылка: | https://doi.org/10.1038/s41387-022-00199-y |