Targeting Wnt/β-catenin-mediated upregulation of oncogenic NLGN3 suppresses cancer stem cells in glioblastoma
Abstract Glioblastoma (GBM) is the most malignant tumor in brain and is highly resistant to therapy. Clinical evidence suggests increased number of cancer stem cells (CSCs) may contribute to the failure of conventional therapies, but the mechanisms associated with acquisition of CSC properties in GB...
Main Authors: | Eun-Jin Yun, Donghwi Kim, Sangwoo Kim, Jer-Tsong Hsieh, Seung Tae Baek |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-07-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05967-x |
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