Low-dose mitotane-induced neurological and endocrinological complication in a 5-year-old girl with adrenocortical carcinoma

Low-dose mitotane-induced neurological and endocrinological complication in a 5-year-old girl with adrenocortical carcinoma

Mitotane is an adrenolytic drug that exhibits therapeutic effects within a narrow target range (14–20 μg/dL). Various complications develop if the upper limit is exceeded. We present the case of a 5-year-old girl with breast development, acne, and pubic hair who was diagnosed with an adrenal mass th...

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Bibliographic Details
Main Authors: You Joung Heo, Jae Ho Yoo, Yun Soo Choe, Sang Hee Park, Seung Bok Lee, Hyun A Kim, Jung Yoon Choi, Young Ah Lee, Byung Chan Lim, Hee Won Chueh
Format: Article
Language:English
Published: Korean Society of Pediatric Endocrinology 2022-09-01
Series:Annals of Pediatric Endocrinology & Metabolism
Subjects:
adrenocortical carcinoma
mitotane
adverse effects
pediatrics
Online Access:http://e-apem.org/upload/pdf/apem-2142044-022.pdf

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