Intestinal Claudin-7 deficiency impacts the intestinal microbiota in mice with colitis

Intestinal Claudin-7 deficiency impacts the intestinal microbiota in mice with colitis

Abstract Background Intestinal epithelial cells form a physical barrier that protects the intestine against the intestinal microbiota through tight junctions (TJs) and adhesive junctions, while barrier disruption may lead to inflammatory bowel disease (IBD). Claudin-7 (Cldn7) has been implicated in...

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Bibliographic Details
Main Authors: Yuhan Ding, Kun Wang, Chang Xu, Mengdi Hao, Huimin Li, Lei Ding
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Gastroenterology
Subjects:
Claudin-7
Colitis
Intestinal microbiota
Tight junction
Microbiota dysbiosis
Online Access:https://doi.org/10.1186/s12876-022-02100-8

Internet

https://doi.org/10.1186/s12876-022-02100-8

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