Improvement of early exercise combined with electrical stimulation of neuromuscular system on ICU acquired weakness in patients with severe pneumonia
Objective To investigate the effect of early activity combined with electrical stimulation of neuromuscular system in improving intensive care unit (ICU)-acquired weakness (ICU-AW) patients with severe pneumonia. Methods A total of 150 patients with ICU-AW caused by severe pneumonia admitted to emer...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2024-02-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-2-242.pdf |
| _version_ | 1827373695690080256 |
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| author | LU Yunxia, FENG Yue, JIANG Jinxia, YANG Shuai |
| author_facet | LU Yunxia, FENG Yue, JIANG Jinxia, YANG Shuai |
| author_sort | LU Yunxia, FENG Yue, JIANG Jinxia, YANG Shuai |
| collection | DOAJ |
| description | Objective To investigate the effect of early activity combined with electrical stimulation of neuromuscular system in improving intensive care unit (ICU)-acquired weakness (ICU-AW) patients with severe pneumonia. Methods A total of 150 patients with ICU-AW caused by severe pneumonia admitted to emergency intensive care unit(EICU) in a tertiary hospital in Shanghai were enrolled as the study subjects, and randomly divided into control group (75 cases) and combined group (75 cases). The control group took early exercise, and the combination group was given early exercise plus electrical stimulation of neuromuscular system. The recovery from mechanical ventilation (ICU length of stay, duration of mechanical ventilation, weaning extubation rate, ICU rollout rate), lung function [forced vital capacity (FVC), forced expiratory volume in the 1 s (FEV1)/FVC, massive inspiratory pressure (MIP)],muscle strength[Medical Research Council (MRC) score], disease severity[acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ)], and complications were compared between the two groups. Results The ICU length of stay and mechanical ventilation time in the combined group were significantly lower than those in the control group (P＜0.05). After intervention, FVC, FEV1/FVC, MIP and MRC scores in the two groups were significantly increased(P＜0.05), and compared with the control group, the combined group was significantly increased(P＜0.05). After intervention, APACHE Ⅱ score was significantly reduced in the two groups(P＜0.05), and compared with the control group, APACHE Ⅱ score in combined group were significantly reduced (P＜0.05). The complication rate in the combined group (9.33%) was significantly lower than that of control group (24.00%) (P＜0.05). Conclusions Early exercise combined with neuromuscular electrical stimulation in patients with severe pneumonia ICU-AW can effectively promote recovery of patients because of improved lung function. This therapy is proved to be be safe and effective. |
| first_indexed | 2024-03-08T11:21:02Z |
| format | Article |
| id | doaj.art-07bfb8ae1ecb4c2983d517dce4fbb6ad |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T11:21:02Z |
| publishDate | 2024-02-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-07bfb8ae1ecb4c2983d517dce4fbb6ad2024-01-26T09:27:35ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252024-02-0144224224610.16352/j.issn.1001-6325.2024.02.0242Improvement of early exercise combined with electrical stimulation of neuromuscular system on ICU acquired weakness in patients with severe pneumoniaLU Yunxia, FENG Yue, JIANG Jinxia, YANG Shuai01. School of Medicine, Tongji University, Shanghai 200092; ;2. Emergency Intensive Care Unit (EICU); ;3. Emergency Department, the 10th People's Hospital Affiliated to Tongji University, Shanghai 200072; ;4. Rehabilitation Department, Shanghai Institute of Traumatology and Orthopedics, Shanghai 200020, ChinaObjective To investigate the effect of early activity combined with electrical stimulation of neuromuscular system in improving intensive care unit (ICU)-acquired weakness (ICU-AW) patients with severe pneumonia. Methods A total of 150 patients with ICU-AW caused by severe pneumonia admitted to emergency intensive care unit(EICU) in a tertiary hospital in Shanghai were enrolled as the study subjects, and randomly divided into control group (75 cases) and combined group (75 cases). The control group took early exercise, and the combination group was given early exercise plus electrical stimulation of neuromuscular system. The recovery from mechanical ventilation (ICU length of stay, duration of mechanical ventilation, weaning extubation rate, ICU rollout rate), lung function [forced vital capacity (FVC), forced expiratory volume in the 1 s (FEV1)/FVC, massive inspiratory pressure (MIP)],muscle strength[Medical Research Council (MRC) score], disease severity[acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ)], and complications were compared between the two groups. Results The ICU length of stay and mechanical ventilation time in the combined group were significantly lower than those in the control group (P＜0.05). After intervention, FVC, FEV1/FVC, MIP and MRC scores in the two groups were significantly increased(P＜0.05), and compared with the control group, the combined group was significantly increased(P＜0.05). After intervention, APACHE Ⅱ score was significantly reduced in the two groups(P＜0.05), and compared with the control group, APACHE Ⅱ score in combined group were significantly reduced (P＜0.05). The complication rate in the combined group (9.33%) was significantly lower than that of control group (24.00%) (P＜0.05). Conclusions Early exercise combined with neuromuscular electrical stimulation in patients with severe pneumonia ICU-AW can effectively promote recovery of patients because of improved lung function. This therapy is proved to be be safe and effective.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-2-242.pdficu acquired weakness|severe pneumonia|electrical stimulation of neuromuscular system|early exercise |
| spellingShingle | LU Yunxia, FENG Yue, JIANG Jinxia, YANG Shuai Improvement of early exercise combined with electrical stimulation of neuromuscular system on ICU acquired weakness in patients with severe pneumonia Jichu yixue yu linchuang icu acquired weakness|severe pneumonia|electrical stimulation of neuromuscular system|early exercise |
| title | Improvement of early exercise combined with electrical stimulation of neuromuscular system on ICU acquired weakness in patients with severe pneumonia |
| title_full | Improvement of early exercise combined with electrical stimulation of neuromuscular system on ICU acquired weakness in patients with severe pneumonia |
| title_fullStr | Improvement of early exercise combined with electrical stimulation of neuromuscular system on ICU acquired weakness in patients with severe pneumonia |
| title_full_unstemmed | Improvement of early exercise combined with electrical stimulation of neuromuscular system on ICU acquired weakness in patients with severe pneumonia |
| title_short | Improvement of early exercise combined with electrical stimulation of neuromuscular system on ICU acquired weakness in patients with severe pneumonia |
| title_sort | improvement of early exercise combined with electrical stimulation of neuromuscular system on icu acquired weakness in patients with severe pneumonia |
| topic | icu acquired weakness|severe pneumonia|electrical stimulation of neuromuscular system|early exercise |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-2-242.pdf |
| work_keys_str_mv | AT luyunxiafengyuejiangjinxiayangshuai improvementofearlyexercisecombinedwithelectricalstimulationofneuromuscularsystemonicuacquiredweaknessinpatientswithseverepneumonia |