Chronic bronchitis and current smoking are associated with more goblet cells in moderate to severe COPD and smokers without airflow obstruction.

BACKGROUND:Goblet cell hyperplasia is a classic but variable pathologic finding in COPD. Current literature shows that smoking is a risk factor for chronic bronchitis but the relationship of these clinical features to the presence and magnitude of large airway goblet cell hyperplasia has not been we...

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Bibliographic Details
Main Authors: Victor Kim, Michelle Oros, Heba Durra, Steven Kelsen, Mark Aksoy, William D Cornwell, Thomas J Rogers, Gerard J Criner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4315442?pdf=render