The Influence of Palmatine Isolated from <i>Berberis sibirica Radix</i> on Pentylenetetrazole-Induced Seizures in Zebrafish

The Influence of Palmatine Isolated from <i>Berberis sibirica Radix</i> on Pentylenetetrazole-Induced Seizures in Zebrafish

Palmatine (PALM) and berberine (BERB) are widely identified isoquinoline alkaloids among the representatives of the Berberidaceae botanical family. The antiseizure activity of BERB was shown previously in experimental epilepsy models. We assessed the effect of PALM in a pentylenetetrazole (PTZ)-indu...

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Bibliographic Details
Main Authors: Kinga Gawel, Wirginia Kukula-Koch, Dorota Nieoczym, Katarzyna Stepnik, Wietske van der Ent, Nancy Saana Banono, Dominik Tarabasz, Waldemar A. Turski, Camila V. Esguerra
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
<i>Berberis sibirica radix</i>
palmatine
berberine
isolation
zebrafish
pentylenetetrazole
Online Access:https://www.mdpi.com/2073-4409/9/5/1233

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