Perphenazine Attenuates the Pro-Inflammatory Responses in Mouse Models of Th2-Type Allergic Dermatitis

Perphenazine Attenuates the Pro-Inflammatory Responses in Mouse Models of Th2-Type Allergic Dermatitis

Developing dermatitis therapeutics has been faced with challenges including adverse effects of topical steroid and high cost of new developing drugs. Here, we found the expression levels of dopamine receptor D2 is higher in skin biopsies of dermatitis patients and an oxazolone-induced animal model o...

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Bibliographic Details
Main Authors: Min-Jeong Heo, Soo Young Choi, Chanmi Lee, Yeong Min Choi, In-sook An, Seunghee Bae, Sungkwan An, Jin Hyuk Jung
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
dopamine receptor D2
perphenazine
dermatitis
drug repurposing
Online Access:https://www.mdpi.com/1422-0067/21/9/3241

Internet

https://www.mdpi.com/1422-0067/21/9/3241

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