QSAR study of antiproliferative drug against A549 by GA-MLR and SW-MLR methods

QSAR study of antiproliferative drug against A549 by GA-MLR and SW-MLR methods

Quantitative structure-activity relationship (QSAR) is the most extensively used computational methodology for analogue-based design. In this research, QSAR model was used to predict antiproliferative properties of 4-(2-fluorophenoxy) quinoline derivatives against A549(human lung adenocarcinoma). Fo...

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Bibliographic Details
Main Authors: Somayeh Alimohammadi, Aliasghar Hamidi, Parinaz Pargolghasemi, Nasim Nourani, Mir Saleh Hoseininezhad-Namin
Format: Article
Language:English
Published: Iranian Chemical Science and Technologies Association 2019-11-01
Series:Chemical Review and Letters
Subjects:
lung cancer
quinoline derivative
multiple linear regressions
genetic algorithm
Online Access:http://www.chemrevlett.com/article_103559_c1335f2635a9e2498ca321bd5e7b0e99.pdf

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