Brain damage led to decrease of nitric oxide content in the hippocampus of rats: Investigation by EPR spectroscopy
Direct measurements of the content of nitric oxide (NO) by the method of spectroscopy of electron paramagnetic resonance were performed. It was found that NO production in hippocampus tissues decreased to 46% after 5 h of ischemic stroke as compared to the control group and remained at the same leve...
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| Format: | Article |
| Language: | English |
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Kazan Federal University
2018-12-01
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| Series: | Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki |
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| Online Access: | https://kpfu.ru/brain-damage-led-to-decrease-of-nitric-oxide_382302.html |
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| author | G.G. Yafarova V.V. Andrianov S.G. Pashkevich Ju.P. Stukach M.O. Dosina T.Kh. Bogodvid V.A. Kulchitsky Kh.L. Gainutdinov |
| author_facet | G.G. Yafarova V.V. Andrianov S.G. Pashkevich Ju.P. Stukach M.O. Dosina T.Kh. Bogodvid V.A. Kulchitsky Kh.L. Gainutdinov |
| author_sort | G.G. Yafarova |
| collection | DOAJ |
| description | Direct measurements of the content of nitric oxide (NO) by the method of spectroscopy of electron paramagnetic resonance were performed. It was found that NO production in hippocampus tissues decreased to 46% after 5 h of ischemic stroke as compared to the control group and remained at the same level after 72 h. Following the hemorrhagic stroke, the level of NO production in the hippocampus decreased to 32% after 5 h of hemorrhagic stroke of the control level. After 72 hours of hemorrhagic stroke NO production was higher than after 5 h and amounted to 48% of the level of intact animals. |
| first_indexed | 2024-03-13T07:13:34Z |
| format | Article |
| id | doaj.art-07c960c43bbc436db624b186844c2b9c |
| institution | Directory Open Access Journal |
| issn | 2542-064X 2500-218X |
| language | English |
| last_indexed | 2024-03-13T07:13:34Z |
| publishDate | 2018-12-01 |
| publisher | Kazan Federal University |
| record_format | Article |
| series | Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki |
| spelling | doaj.art-07c960c43bbc436db624b186844c2b9c2023-06-05T13:47:09ZengKazan Federal UniversityUčënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki2542-064X2500-218X2018-12-011604654662Brain damage led to decrease of nitric oxide content in the hippocampus of rats: Investigation by EPR spectroscopyG.G. Yafarova0V.V. Andrianov1S.G. Pashkevich2Ju.P. Stukach3M.O. Dosina4T.Kh. Bogodvid5V.A. Kulchitsky6Kh.L. Gainutdinov7Kazan Federal University, Kazan, 420008 Russia; Zavoisky Physical-Technical Institute, FRC Kazan Scientific Center of Russian Academy of Sciences, Kazan, 420034 RussiaKazan Federal University, Kazan, 420008 Russia; Zavoisky Physical-Technical Institute, FRC Kazan Scientific Center of Russian Academy of Sciences, Kazan, 420034 RussiaInstitute of Physiology of National Academy of Sciences of Belarus, Minsk, 220072 Republic of BelarusInstitute of Physiology of National Academy of Sciences of Belarus, Minsk, 220072 Republic of BelarusInstitute of Physiology of National Academy of Sciences of Belarus, Minsk, 220072 Republic of BelarusKazan Federal University, Kazan, 420008 Russia; Volga Region State Academy of Physical Culture, Kazan, 420010 RussiaInstitute of Physiology of National Academy of Sciences of Belarus, Minsk, 220072 Republic of BelarusKazan Federal University, Kazan, 420008 Russia; Zavoisky Physical-Technical Institute, FRC Kazan Scientific Center of Russian Academy of Sciences, Kazan, 420034 RussiaDirect measurements of the content of nitric oxide (NO) by the method of spectroscopy of electron paramagnetic resonance were performed. It was found that NO production in hippocampus tissues decreased to 46% after 5 h of ischemic stroke as compared to the control group and remained at the same level after 72 h. Following the hemorrhagic stroke, the level of NO production in the hippocampus decreased to 32% after 5 h of hemorrhagic stroke of the control level. After 72 hours of hemorrhagic stroke NO production was higher than after 5 h and amounted to 48% of the level of intact animals.https://kpfu.ru/brain-damage-led-to-decrease-of-nitric-oxide_382302.htmlnitric oxideischemic brain strokehemorrhagic brain strokehippocampuselectron paramagnetic resonance |
| spellingShingle | G.G. Yafarova V.V. Andrianov S.G. Pashkevich Ju.P. Stukach M.O. Dosina T.Kh. Bogodvid V.A. Kulchitsky Kh.L. Gainutdinov Brain damage led to decrease of nitric oxide content in the hippocampus of rats: Investigation by EPR spectroscopy Učënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki nitric oxide ischemic brain stroke hemorrhagic brain stroke hippocampus electron paramagnetic resonance |
| title | Brain damage led to decrease of nitric oxide content in the hippocampus of rats: Investigation by EPR spectroscopy |
| title_full | Brain damage led to decrease of nitric oxide content in the hippocampus of rats: Investigation by EPR spectroscopy |
| title_fullStr | Brain damage led to decrease of nitric oxide content in the hippocampus of rats: Investigation by EPR spectroscopy |
| title_full_unstemmed | Brain damage led to decrease of nitric oxide content in the hippocampus of rats: Investigation by EPR spectroscopy |
| title_short | Brain damage led to decrease of nitric oxide content in the hippocampus of rats: Investigation by EPR spectroscopy |
| title_sort | brain damage led to decrease of nitric oxide content in the hippocampus of rats investigation by epr spectroscopy |
| topic | nitric oxide ischemic brain stroke hemorrhagic brain stroke hippocampus electron paramagnetic resonance |
| url | https://kpfu.ru/brain-damage-led-to-decrease-of-nitric-oxide_382302.html |
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