Heparan sulfate negatively regulates intestinal stem cell proliferation in Drosophila adult midgut

Heparan sulfate negatively regulates intestinal stem cell proliferation in Drosophila adult midgut

Tissue homeostasis is maintained by differentiated progeny of residential stem cells. Both extrinsic signals and intrinsic factors play critical roles in the proliferation and differentiation of adult intestinal stem cells (ISCs). However, how extrinsic signals are transduced into ISCs still remains...

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Bibliographic Details
Main Authors: Hubing Ma, Huiqing Zhao, Fuli Liu, Hang Zhao, Ruiyan Kong, Lin Shi, Min Wei, Zhouhua Li
Format: Article
Language:English
Published: The Company of Biologists 2019-10-01
Series:Biology Open
Subjects:
intestinal stem cell
heparan sulfate
drosophila
tissue homeostasis
dpp signaling
Online Access:http://bio.biologists.org/content/8/10/bio047126

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