Distribution characteristics of selenium, cadmium and arsenic in rice grains and their genetic dissection by genome-wide association study
High selenium (Se) and low cadmium (Cd) and arsenic (As) contents in rice grains were good for human health. The genetic basis and relationship of Se, Cd and As concentrations in rice grains are still largely unknown. In the present study, large variations were observed in Se, Cd and As concentratio...
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Genetics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2022.1007896/full |
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| author | Wenxi Wang Wenxi Wang Fan Zhang Dapu Liu Kai Chen Bin Du Xianjin Qiu Jianlong Xu Jianlong Xu Jianlong Xu Danying Xing |
| author_facet | Wenxi Wang Wenxi Wang Fan Zhang Dapu Liu Kai Chen Bin Du Xianjin Qiu Jianlong Xu Jianlong Xu Jianlong Xu Danying Xing |
| author_sort | Wenxi Wang |
| collection | DOAJ |
| description | High selenium (Se) and low cadmium (Cd) and arsenic (As) contents in rice grains were good for human health. The genetic basis and relationship of Se, Cd and As concentrations in rice grains are still largely unknown. In the present study, large variations were observed in Se, Cd and As concentrations in brown and milled rice in normal and Se treatment conditions in 307 rice accessions from 3K Rice Genomes Project. Se fertilizer treatment greatly increased Se concentrations but had no obvious changes in concentrations of Cd and As both in brown and milled rice. Total of 237 QTL were identified for Se, Cd and As concentrations in brown and milled rice in normal and Se treatment conditions as well as ratio of concentrations under Se treatment to normal conditions. Only 19 QTL (13.4%) were mapped for concentrations of Se and Cd, Se and As, and Se, Cd and As in the same or adjacent regions, indicating that most Se concentration QTL are independent of Cd and As concentration QTL. Forty-three favorable alleles were identified for 40 candidate genes by gene-based association study and haplotype analysis in 14 important QTL regions. Se-enriched rice variety will be developed by pyramiding favorable alleles at different Se QTL and excluding undesirable alleles at Cd and As QTL, or combining favorable alleles at Se QTL with the alleles at Se-sensitive QTL by marker-assisted selection. |
| first_indexed | 2024-04-11T16:43:21Z |
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| institution | Directory Open Access Journal |
| issn | 1664-8021 |
| language | English |
| last_indexed | 2024-04-11T16:43:21Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Genetics |
| spelling | doaj.art-07cfe8a165414ba3aeabcd3f044765412022-12-22T04:13:37ZengFrontiers Media S.A.Frontiers in Genetics1664-80212022-10-011310.3389/fgene.2022.10078961007896Distribution characteristics of selenium, cadmium and arsenic in rice grains and their genetic dissection by genome-wide association studyWenxi Wang0Wenxi Wang1Fan Zhang2Dapu Liu3Kai Chen4Bin Du5Xianjin Qiu6Jianlong Xu7Jianlong Xu8Jianlong Xu9Danying Xing10College of Economy and Management, Hubei University of Technology, Wuhan, ChinaMARA Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River (Co-construction by Ministry and Province), College of Agriculture, Yangtze University, Jingzhou, ChinaInstitute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing, ChinaInstitute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing, ChinaShenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, ChinaMARA Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River (Co-construction by Ministry and Province), College of Agriculture, Yangtze University, Jingzhou, ChinaMARA Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River (Co-construction by Ministry and Province), College of Agriculture, Yangtze University, Jingzhou, ChinaInstitute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing, ChinaShenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, ChinaNational Nanfan Research Institute (Sanya), Chinese Academy of Agricultural Sciences, Sanya, ChinaMARA Key Laboratory of Sustainable Crop Production in the Middle Reaches of the Yangtze River (Co-construction by Ministry and Province), College of Agriculture, Yangtze University, Jingzhou, ChinaHigh selenium (Se) and low cadmium (Cd) and arsenic (As) contents in rice grains were good for human health. The genetic basis and relationship of Se, Cd and As concentrations in rice grains are still largely unknown. In the present study, large variations were observed in Se, Cd and As concentrations in brown and milled rice in normal and Se treatment conditions in 307 rice accessions from 3K Rice Genomes Project. Se fertilizer treatment greatly increased Se concentrations but had no obvious changes in concentrations of Cd and As both in brown and milled rice. Total of 237 QTL were identified for Se, Cd and As concentrations in brown and milled rice in normal and Se treatment conditions as well as ratio of concentrations under Se treatment to normal conditions. Only 19 QTL (13.4%) were mapped for concentrations of Se and Cd, Se and As, and Se, Cd and As in the same or adjacent regions, indicating that most Se concentration QTL are independent of Cd and As concentration QTL. Forty-three favorable alleles were identified for 40 candidate genes by gene-based association study and haplotype analysis in 14 important QTL regions. Se-enriched rice variety will be developed by pyramiding favorable alleles at different Se QTL and excluding undesirable alleles at Cd and As QTL, or combining favorable alleles at Se QTL with the alleles at Se-sensitive QTL by marker-assisted selection.https://www.frontiersin.org/articles/10.3389/fgene.2022.1007896/fullriceseleniumcadmiumarsenicgenome-wide association studyquantitative trait locus/loci (QTL) |
| spellingShingle | Wenxi Wang Wenxi Wang Fan Zhang Dapu Liu Kai Chen Bin Du Xianjin Qiu Jianlong Xu Jianlong Xu Jianlong Xu Danying Xing Distribution characteristics of selenium, cadmium and arsenic in rice grains and their genetic dissection by genome-wide association study Frontiers in Genetics rice selenium cadmium arsenic genome-wide association study quantitative trait locus/loci (QTL) |
| title | Distribution characteristics of selenium, cadmium and arsenic in rice grains and their genetic dissection by genome-wide association study |
| title_full | Distribution characteristics of selenium, cadmium and arsenic in rice grains and their genetic dissection by genome-wide association study |
| title_fullStr | Distribution characteristics of selenium, cadmium and arsenic in rice grains and their genetic dissection by genome-wide association study |
| title_full_unstemmed | Distribution characteristics of selenium, cadmium and arsenic in rice grains and their genetic dissection by genome-wide association study |
| title_short | Distribution characteristics of selenium, cadmium and arsenic in rice grains and their genetic dissection by genome-wide association study |
| title_sort | distribution characteristics of selenium cadmium and arsenic in rice grains and their genetic dissection by genome wide association study |
| topic | rice selenium cadmium arsenic genome-wide association study quantitative trait locus/loci (QTL) |
| url | https://www.frontiersin.org/articles/10.3389/fgene.2022.1007896/full |
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